Results 21 to 30 of about 74,045 (223)

PTSD: from neurobiology to pharmacological treatments

open access: yesEuropean Journal of Psychotraumatology, 2016
Posttraumatic stress disorder (PTSD) is a chronic debilitating psychiatric disorder characterized by symptoms of re-experience, avoidance, and hyperarousal that can arise immediately or many years after exposure to a traumatic event and injury.
Benjamin Kelmendi   +5 more
doaj   +1 more source

Blockade of alpha 2-adrenergic receptors in prelimbic cortex: impact on cocaine self-administration in adult spontaneously hypertensive rats following adolescent atomoxetine treatment [PDF]

open access: yes, 2017
RATIONALE: Research with the spontaneously hypertensive rat (SHR) model of attention deficit/hyperactivity disorder demonstrated that chronic methylphenidate treatment during adolescence increased cocaine self-administration established during adulthood ...
Baskin, Britahny M.   +3 more
core   +1 more source

Loss of Sympathetic Nerves in Spleens from Patients with End Stage Sepsis

open access: yesFrontiers in Immunology, 2017
The spleen is an important site for central regulation of immune function by noradrenergic sympathetic nerves, but little is known about this major region of neuroimmune communication in humans.
Donald B. Hoover   +7 more
doaj   +1 more source

Anoxia at Birth Induces Behaviorally-Relevant Changes in alpha2-Noradrenergic Receptor Binding in the Adult Rat

open access: yesMcGill Journal of Medicine, 2020
Evidence suggests that Caesarean section birth in the rat, with or without an additional period of anoxia, results in long-term changes in brain catecholamine levels as well as reactivity to stress.
Wayne G. Brake, Shakti Sharma
doaj   +1 more source

Locus coeruleus to basolateral amygdala noradrenergic projections promote anxiety-like behavior [PDF]

open access: yes, 2017
Increased tonic activity of locus coeruleus noradrenergic (LC-NE) neurons induces anxiety-like and aversive behavior. While some information is known about the afferent circuitry that endogenously drives this neural activity and behavior, the downstream ...
Bhatti, Dionnet L.   +6 more
core   +3 more sources

Monoaminergic Neuropathology in Alzheimer's disease [PDF]

open access: yes, 2016
Acknowledgments This work was supported by The Croatian Science Foundation grant. no. IP-2014-09-9730 (“Tau protein hyperphosphorylation, aggregation, and trans-synaptic transfer in Alzheimer’s disease: cerebrospinal fluid analysis and assessment of ...
Bažadona, Danira   +11 more
core   +1 more source

Circulating free fatty acids, insulin, and glucose during chemical stimulation of hypothalamus in rats [PDF]

open access: yes, 1984
The aim of this study was to investigate plasma free fatty acids (FFA), insulin, and blood glucose during chemical stimulation of the lateral and ventromedial hypothalamic areas (LHA and VMH) in rats.
Damsma, G.,   +3 more
core   +1 more source

Rat model of attention-deficit hyperactivity disorder exhibits delayed recovery from acute incisional pain due to impaired descending noradrenergic inhibition

open access: yesScientific Reports, 2023
Chronic pain and attention-deficit hyperactivity disorder (ADHD) frequently coexist. However, the common pathology is still unclear. Attenuated noradrenergic endogenous analgesia can produce acute pain chronification, and dysfunction of noradrenergic ...
Takashi Suto   +7 more
doaj   +1 more source

Distribution of catecholamine fibers in the cochlear nucleus of horseshoe bats and mustache bats [PDF]

open access: yes, 1988
The glyoxylic-acid-induced fluorescence technique was applied to demonstrate patterns of catecholaminergic innervation within the auditory brainstem of echolocating bats and the house mouse.
Björklund   +38 more
core   +1 more source

Mirtazapine for the Treatment of Chronic Pruritus

open access: yesMedicines, 2019
Background: Chronic pruritus is a debilitating condition associated with a wide range of dermatologic, systemic and psychogenic etiologies. In patients with chronic pruritus that is refractory to conventional therapy, symptoms can significantly decrease ...
Raveena Khanna   +4 more
doaj   +1 more source

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