Results 11 to 20 of about 10,132 (232)

The Noradrenergic System in Parkinson’s Disease [PDF]

open access: yesFrontiers in Pharmacology, 2020
Nowadays it is well accepted that in Parkinson’s disease (PD), the neurodegenerative process occurs in stages and that damage to other areas precedes the neuronal loss in the substantia nigra pars compacta, which is considered a pathophysiological ...
Elena Paredes-Rodriguez   +8 more
doaj   +2 more sources

The central noradrenergic system: an overview [PDF]

open access: yesAfrican Journal of Psychiatry, 2007
The central noradrenergic system belongs to a group of brainstem neuromodulatory systems previously referred to as the ascending reticular activating system. In this article a heuristic model is presented of the central noradrenergic system depicting the major projections to other cerebral areas, its interactions with other neuromodulatory systems ...
Viljoen, Margaretha, Panzer, Annie
openaire   +5 more sources

Lack of Noradrenergic Modulation of Indirect Semantic Priming

open access: yesBehavioural Neurology, 2009
Norepinephrine and dopamine are both believed to affect signal-to-noise in the cerebral cortex. Dopaminergic agents appear to modulate semantic networks during indirect semantic priming, but do not appear to affect problem solving dependent on access to ...
Jacquelyne S. Cios   +4 more
doaj   +3 more sources

Developmental control of noradrenergic system by SLITRK1 and its implications in the pathophysiology of neuropsychiatric disorders

open access: yesFrontiers in Molecular Neuroscience, 2023
SLITRK1 is a neuronal transmembrane protein with neurite development-and synaptic formation-controlling abilities. Several rare variants of SLITRK1 have been identified and implicated in the pathogenesis of Tourette’s syndrome, trichotillomania, and ...
Minoru Hatayama, Jun Aruga
doaj   +1 more source

Neuromodulation and a Reconceptualization of Autism Spectrum Disorders: Using the Locus Coeruleus Functioning as an Exemplar

open access: yesFrontiers in Neurology, 2018
The Autism Spectrum Disorders (ASD) are a heterogeneous group of developmental disorders. Although, ASD can be reliably diagnosed, the etiology, pathophysiology, and treatment targets remain poorly characterized. While there are many atypical findings in
Eric B. London
doaj   +1 more source

Localisation of NG2 immunoreactive neuroglia cells in the rat locus coeruleus and their plasticity in response to stress [PDF]

open access: yes, 2014
The locus coeruleus (LC) nucleus modulates adaptive behavioural responses to stress and dysregulation of LC neuronal activity is implicated in stress-induced mental illnesses.
Metzger, Friedrich   +22 more
core   +1 more source

Noradrenergic modulation of arousal [PDF]

open access: yesBrain Research Reviews, 2008
Through a highly divergent efferent projection system, the locus coeruleus-noradrenergic system supplies norepinephrine throughout the central nervous system. State-dependent neuronal discharge activity of locus coeruleus neurons has long-suggested a role of this system in the induction of an alert waking state.
openaire   +2 more sources

PTSD: from neurobiology to pharmacological treatments

open access: yesEuropean Journal of Psychotraumatology, 2016
Posttraumatic stress disorder (PTSD) is a chronic debilitating psychiatric disorder characterized by symptoms of re-experience, avoidance, and hyperarousal that can arise immediately or many years after exposure to a traumatic event and injury.
Benjamin Kelmendi   +5 more
doaj   +1 more source

Stimulation of the noradrenergic system enhances and blockade reduces memory for emotional material in man [PDF]

open access: yes, 1999
Background. It is clearly established that emotional events tend to be remembered particularly vividly. The neurobiological substrates of this phenomenon are poorly understood.
O'Carroll, RE   +11 more
core   +1 more source

Loss of Sympathetic Nerves in Spleens from Patients with End Stage Sepsis

open access: yesFrontiers in Immunology, 2017
The spleen is an important site for central regulation of immune function by noradrenergic sympathetic nerves, but little is known about this major region of neuroimmune communication in humans.
Donald B. Hoover   +7 more
doaj   +1 more source

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