Bromoacetate Olefination Protocol for Norbixin and Julia–Kocienski Olefination for Its Ester Syntheses [PDF]
ACS Omega, 2019 A new olefination protocol utilizing ethyl bromoacetate was highlighted, in which magnesium enolate of the ester coupled with C20 dialdehyde 6, and double eliminations of the protected hydroxyl groups and bromine atoms of the coupling bromohydrin product, efficiently produced norbixin 1 after concomitant hydrolysis of the ester.
Dahye Kim +3 more
doaj +5 more sources
Safety and efficacy of cis‐norbixin di‐potassium salt (annatto F) for cats and dogs [PDF]
EFSA Journal, 2017 Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of annatto F (alkali‐processed norbixin, acid ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +26 more
doaj +4 more sources
Anti-Inflammatory Effects and Photo- and Neuro-Protective Properties of BIO203, a New Amide Conjugate of Norbixin, in Development for the Treatment of Age-Related Macular Degeneration (AMD) [PDF]
International Journal of Molecular Sciences, 2023 9′-cis-norbixin (norbixin/BIO201) protects RPE cells against phototoxicity induced by blue light and N-retinylidene-N-retinylethanolamine (A2E) in vitro and preserves visual functions in animal models of age-related macular degeneration (AMD) in ...
Serge Camelo
exaly +4 more sources
Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo. [PDF]
PLoS ONE, 2016 The accumulation of N-retinylidene-N-retinylethanolamine (A2E, a toxic by-product of the visual pigment cycle) in the retinal pigment epithelium (RPE) is a major cause of visual impairment in the elderly.
Valérie Fontaine +10 more
doaj +3 more sources
Determination of bixin and norbixin in meat using liquid chromatography and photodiode array detection [PDF]
Food Additives & Contaminants: Part A, 2009 The development of an analytical method that enables routine analysis of annatto dye, specifically bixin and norbixin, in meat tissue is described. Liquid-solid extraction was carried out using acetonitrile. Analysis was by HPLC with photodiode array detection using two fixed wavelengths (458 and 486 nm). The possibilities of ion trap mass spectrometry
H, Noppe +5 more
core +6 more sources
Safety of annatto E and the exposure to the annatto colouring principles bixin and norbixin (E 160b) when used as a food additive [PDF]
EFSA Journal, 2019 The Scientific Panel on Food Additives and Flavouring (FAF) provides a scientific opinion on the safety evaluation of annatto E and an exposure assessment of the annatto colouring principles bixin and norbixin (E 160b) when used as a food additive ...
EFSA Panel on Food Additives and Flavourings (EFSA FAF Panel) +19 more
doaj +2 more sources
Morphological, Structural, and Thermal Properties of Microbial Carotenoids Microencapsulated by Spray-Drying Using Different Combinations of Wall Materials. [PDF]
J Food SciABSTRACT This study evaluated the spray‐drying encapsulation of carotenoid‐rich extracts produced by Sporidiobolus salmonicolor, with the optimization of a ternary wall system of gum arabic (GA), inulin (IN), and corn starch (ST). Carotenoids were produced in a semi‐continuous bioreactor, extracted with organic solvents, and microencapsulated by spray ...
Griep P +5 more
europepmc +2 more sources
Short communication: Norbixin and bixin partitioning in Cheddar cheese and whey [PDF]
Journal of Dairy Science, 2014 The Cheddar cheese colorant annatto is present in whey and must be removed by bleaching. Chemical bleaching negatively affects the flavor of dried whey ingredients, which has established a need for a better understanding of the primary colorant in annatto, norbixin, along with cheese color alternatives.
T J Smith, M A Drake, Taryn J Smith
exaly +3 more sources
Effect of norbixin-based poly(hydroxybutyrate) membranes on the tendon repair process after tenotomy in rats [PDF]
Acta Cirúrgica Brasileira, 2020 Purpose: To determine the efficacy of norbixin-based poly(hydroxybutyrate) (PHB) membranes for Achilles tendon repair. Methods: Thirty rats were submitted to total tenotomy surgery of the right Achilles tendon and divided into two groups (control and ...
Lízia Daniela e Silva Nascimento +9 more
doaj +5 more sources
The Bioprospecting of Bixa orellana L. for the Selection of Characters with Biological Activity [PDF]
MetabolitesA meta-analysis of 28 sources of information was conducted, considering different variables in Bixa orellana, with the aim of identifying bioprospective variables.
Luz A. Guerrero-Lagunes +7 more
doaj +2 more sources