Safety and efficacy of cis‐norbixin di‐potassium salt (annatto F) for cats and dogs [PDF]
EFSA Journal, 2017 Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of annatto F (alkali‐processed norbixin, acid ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +26 more
doaj +4 more sources
Bromoacetate Olefination Protocol for Norbixin and Julia–Kocienski Olefination for Its Ester Syntheses [PDF]
ACS Omega, 2019 A new olefination protocol utilizing ethyl bromoacetate was highlighted, in which magnesium enolate of the ester coupled with C20 dialdehyde 6, and double eliminations of the protected hydroxyl groups and bromine atoms of the coupling bromohydrin product, efficiently produced norbixin 1 after concomitant hydrolysis of the ester.
Dahye Kim +3 more
doaj +5 more sources
Third- and fifth-order optical nonlinearities of norbixin
Results in Optics, 2022 In this work, we investigated the nonlinear response of norbixin (C24H28O4) in acetone. The third- and fifth-order optical nonlinearities were measured using the conventional Z-scan technique, with 357 fs laser pulses at 1040 nm and low-repetition rate ...
Nefe Jefferson Brito e Silva +6 more
doaj +2 more sources
Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo. [PDF]
PLoS ONE, 2016 The accumulation of N-retinylidene-N-retinylethanolamine (A2E, a toxic by-product of the visual pigment cycle) in the retinal pigment epithelium (RPE) is a major cause of visual impairment in the elderly.
Valérie Fontaine +10 more
doaj +4 more sources
Poly(Hydroxybutyrate) and Norbixin as Biomaterials In Biological Applications
Reviews on Advanced Materials Science, 2018 This review presents the survey of performance of biomaterials prepared using norbixina and poly(hydroxybutyrate) as biomaterials in biological applications. Biomaterials can replace and/or stimulate biological systems that no longer have their functions,
Sousa R. C. +4 more
doaj +2 more sources
Safety of annatto E and the exposure to the annatto colouring principles bixin and norbixin (E 160b) when used as a food additive [PDF]
EFSA Journal, 2019 The Scientific Panel on Food Additives and Flavouring (FAF) provides a scientific opinion on the safety evaluation of annatto E and an exposure assessment of the annatto colouring principles bixin and norbixin (E 160b) when used as a food additive ...
EFSA Panel on Food Additives and Flavourings (EFSA FAF Panel) +19 more
doaj +2 more sources
Structural analysis of unstable norbixin isomers guided by pure shift nuclear magnetic resonance
Magnetic Resonance in Chemistry, Volume 60, Issue 5, Page 504-514, May 2022., 2022 We report the NMR analysis of complex samples obtained during the microwave irradiation/heating of norbixin, which is a potential therapeutic target for age‐related macular degeneration (AMD). We could successfully apply 1D pure shift experiments to record in a reduced amount of time ultrahigh resolution 1H NMR spectra of the norbixin isomer samples ...
Gildas Bertho +9 more
wiley +4 more sources
Bixin, Norbixin and Quercetin and lipid metabolism effects in rabbits [PDF]
, 2001 Flavonoids have been isolated with several biological activities and there are correlations among the consumption of rich foods in flavonoids and heart diseases. The 7-glucosyl-apigenin, 7- bisulfate-apigenin, 7-glucosyl-luteolin, 7-bisulfate-luteolin flavonoids and bixin and norbixin were isolated from urucu seeds.
Lima, Leonardo Ramos Paes +6 more
openaire +5 more sources
Fatores que influenciam a reação de saponificação dos carotenóides presentes no urucum (Bixa orellana L.) Factors that influence saponification reaction in annatto (Bixa orellana L.) carotenoids [PDF]
Ciência e Agrotecnologia, 2009 Conduziu-se este trabalho, com o objetivo de estudar o efeito de diferentes concentrações de KOH (0,6%, 1%, 2%, 3%, 4% e 5%) e temperatura de extração (25ºC, 50°C, 60°C e 70°C) na reação de saponificação dos principais pigmentos de urucum. O progresso da
Pollyanna Ibrahim Silva +2 more
doaj +4 more sources
Anti-Inflammatory Effects and Photo- and Neuro-Protective Properties of BIO203, a New Amide Conjugate of Norbixin, in Development for the Treatment of Age-Related Macular Degeneration (AMD). [PDF]
Int J Mol Sci, 2023 9′-cis-norbixin (norbixin/BIO201) protects RPE cells against phototoxicity induced by blue light and N-retinylidene-N-retinylethanolamine (A2E) in vitro and preserves visual functions in animal models of age-related macular degeneration (AMD) in ...
Fontaine V +14 more
europepmc +2 more sources