Beyond AREDS Formulations, What Is Next for Intermediate Age-Related Macular Degeneration (iAMD) Treatment? Potential Benefits of Antioxidant and Anti-inflammatory Apocarotenoids as Neuroprotectors. [PDF]
Age‐related macular degeneration (AMD) is the commonest cause of severe visual loss and blindness in developed countries among individuals aged 60 and older. AMD slowly progresses from early AMD to intermediate AMD (iAMD) and ultimately late‐stage AMD. Late AMD encompasses either neovascular AMD (nAMD) or geographic atrophy (GA).
Camelo S +4 more
europepmc +2 more sources
Fatores que influenciam a reação de saponificação dos carotenóides presentes no urucum (Bixa orellana L.) Factors that influence saponification reaction in annatto (Bixa orellana L.) carotenoids [PDF]
Conduziu-se este trabalho, com o objetivo de estudar o efeito de diferentes concentrações de KOH (0,6%, 1%, 2%, 3%, 4% e 5%) e temperatura de extração (25ºC, 50°C, 60°C e 70°C) na reação de saponificação dos principais pigmentos de urucum. O progresso da
Pollyanna Ibrahim Silva +2 more
doaj +3 more sources
Bixin, Norbixin and Quercetin and lipid metabolism effects in rabbits [PDF]
Flavonoids have been isolated with several biological activities and there are correlations among the consumption of rich foods in flavonoids and heart diseases. The 7-glucosyl-apigenin, 7- bisulfate-apigenin, 7-glucosyl-luteolin, 7-bisulfate-luteolin flavonoids and bixin and norbixin were isolated from urucu seeds.
Lima, Leonardo Ramos Paes +6 more
openaire +4 more sources
Shelf-Life Extension of Chicken Fillets Using Flaxseed Mucilage Coatings Incorporated With Bixin-Allicin or Bixin-Orange Peel Essential Oil Nanoemulsions. [PDF]
Flaxseed mucilage incorporated with bixin‐allicin or bixin‐orange peel oil nanoemulsions significantly extended the shelf‐life and quality of fresh chicken fillets. ABSTRACT This study evaluated the properties of orange peel essential oil (OPE) and allicin emulsions and their efficacy in flaxseed mucilage‐bixin (FM‐B) coating for preserving chicken ...
Hashemi N, Milani E, Koocheki A.
europepmc +2 more sources
Bixin and Norbixin Have Opposite Effects on Glycemia, Lipidemia, and Oxidative Stress in Streptozotocin-Induced Diabetic Rats [PDF]
The present study investigated the effects of oral administration of annatto carotenoids (bixin (BIX) and norbixin (NBIX)) on glucose levels, lipid profiles, and oxidative stress parameters in streptozotocin (STZ)-induced diabetic rats.
Miguel Roehrs +8 more
doaj +2 more sources
Carotenoides bixina e norbixina extraídos do urucum (Bixa orellana L.) como antioxidantes em produtos cárneos Carotenoids bixin and norbixin from annatto (Bixa orellana L.) as antioxidants in meat products [PDF]
A oxidação lipídica é uma das principais alterações que acometem os derivados cárneos em razão da composição química rica em lipídios e íons ferro, utilização de processos térmicos e de moagem, além do frequente uso do cloreto de sódio, um reconhecido ...
Carlos Eduardo Rocha Garcia +4 more
doaj +3 more sources
A2E-induced inflammation and angiogenesis in RPE cells in vitro are modulated by PPAR-α, -β/δ, -γ, and RXR antagonists and by norbixin. [PDF]
International audienceN-retinylidene-N-retinylethanolamine (A2E) plays a central role in age-related macular degeneration (AMD) by inducing angiogenesis and inflammation.
Fontaine V +11 more
europepmc +2 more sources
The Thermo-Optic Effect in Norbixin: Characterization by Z‑Scan and Self-Phase Modulation under CW Laser [PDF]
Nefe Jefferson Brito Silva +8 more
doaj +2 more sources
Effect of low intensity photobiomodulation associated with norbixin-based poly (hydroxybutyrate) membrane on post-tenotomy tendon repair. In vivo study [PDF]
Purpose: To evaluate the in vivo response of photobiomodulation therapy associated with norbixin-based poly(hydroxybutyrate) membrane (PHB) in tenotomized calcaneal tendon.
Lízia Daniela e Silva Nascimento +7 more
doaj +2 more sources
Systemic administration of the di-apocarotenoid norbixin (BIO201) is neuroprotective, preserves photoreceptor function and inhibits A2E and lipofuscin accumulation in animal models of age-related macular degeneration and Stargardt disease. [PDF]
International audienceAtrophic A\age-related macular degeneration (AMD) and Stargardt disease (STGD) are major blinding diseases affecting millions of patients worldwide, but no treatment is available.
Fontaine V +13 more
europepmc +2 more sources

