Results 121 to 130 of about 838,377 (285)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

A role for P selectin in complement-independent neutrophil-mediated glomerular injury

, 1994
A role for P selectin in complement-independent neutrophil-mediated glomerular injury. Neutrophil recruitment and lung injury following complement activation have been demonstrated to be dependent on endothelial expression of P selectin.
Huang, Xiao Ru, Tipping, Peter G., Holdsworth, Stephen R., Berndt, Michael C.   +3 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A Newly Described Control Mechanism of Complement Activation in Patients with Mixed Cryoglobulinemia (Cryoglobulins and Complement)

, 1980
Levels in serum of components of complement were studied in a group of 10 patients with mixed cryoglobulinemia. The profiles found in most patients showed decreased levels of the early complement components C1, C4, and C2, with normal levels of C3 ...
de Rojas, Marta Patarroyo, Haydey, Richard P., Gigli, Irma   +2 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Immunohistochemical demonstration of membrane cofactor protein (MCP) of complement in normal and diseased kidney tissues

, 1993
SUMMARY The immunohistochemically stained membrane cofactor protein of complement (MCP/CD46), one of the complement regulatory proteins, was up-regulated in some diseased kidney tissues.
H OKADA, M YAMASHINA, J P ATKINSON, T IKUNO, M ENDOH, K FUNAHASHI, T YASUGI, H OHI   +7 more
core   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Título: Programa de Historia Sagrada

, 1887
Con portada propia: Programa de historia sagrada, p. 7-12Precede al tít. : Escuela Normal Superior de Maestros de SantiagoCon port. propia : Programa de historia sagrada p.
Guerrero Montalbán y Vázquez, Santiago, Escuela Normal Superior de Maestros de Santiago   +1 more
core  

MAC deposition of human complement-competent and -compromised sera in the three individual complement pathways.

, 2013
Values are represented as means±SD of 3 independent experiments. Normal complement function is above 69, 10 and 30 units for the CP, LP and AP respectively, as indicated in the table.
Gunnar Houen (135401), Inga Laursen (455728), Peter Højrup (455729), Esin Güven (455727), Karen Duus (88867)   +4 more
core   +1 more source