Results 101 to 110 of about 838,377 (285)

Dextran sulfate activates contact system and mediates arterial hypotension via B2 kinin receptors [PDF]

open access: yes, 1994
To define some of the mechanisms underlying dextran sulfate (DXS)-induced hypotension, we investigated the effects of either the plasma kallikrein inhibitor des-Pro2-[Arg15] aprotinin (BAY x 4620) or the specific bradykinin B2-receptor antagonist Hoe-140
Cheronis, J. C.   +16 more
core   +1 more source

Clinical Significance of Detection of Coagulation Indexes, Immune Factors and Inflammatory Factors in Patients with Pregnancy-Induced Hypertension Syndrome in China

open access: yesIranian Journal of Public Health, 2019
Background: To investigate the clinical significance of monitoring the coagulation indexes, immune factors and inflammatory factors in pregnancy-induced hypertension syndrome (PIH).
Fengmei SHI, Aijun YU, Limei YUAN
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice

open access: yesJournal of Neuroinflammation, 2009
Background Complement represents a crucial mediator of neuroinflammation and neurodegeneration after traumatic brain injury. The role of the terminal complement activation pathway, leading to generation of the membrane attack complex (MAC), has not been ...
Beauchamp Kathryn   +11 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

The influence of p-regular class sizes on normal subgroups [PDF]

open access: yes, 2013
Let G be a finite group and N be a normal subgroup of G and suppose that the p-regular elements of N have exactly two G-conjugacy class sizes. It is shown that N is solvable and that if H is a p-complement of N, then either H is abelian or H is the ...
Beltran, A.   +5 more
core   +1 more source

Low serum complements in idiopathic inflammatory myositis: clinical features and impact on the prognosis

open access: yesImmunological Medicine
This study investigated the clinical features and prognostic relevance of decreased serum complement levels in patients with idiopathic inflammatory myositis (IIM). The clinical information of IIM patients with less than normal serum complement levels (L-
Shun Nomura   +5 more
doaj   +1 more source

SIGNIFICANCE OF COMPLEMENT PROFILE AND COMPLEMENT RECEPTOR 1 EXPRESSION IN RBC AND KIDNEY TISSUE IN IMMUNE COMPLEX MEDIATED DISEASE

open access: yesJournal of Nepal Medical Association, 2003
A study was conducted to evaluate role of complement proteins and complement receptor 1 (CR1) in pathogenesis of Systemic lupus erythematosus (SLE) and Immune complex (IC) mediated glomerulonephritis. C3, C4, C3d and CH100 in serum, CR1 in renal biopsies
Nirmal Baral, M Lamsal, L M Shrivastava
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

補体学入門 : Cold Activation現象の発見から現在の問題点まで(自然科学系)

open access: yes, 1997
This short review is for beginners in complementology. The complement system is composed of 30 kinds of physiological proteins: 14 serum complement components; 6 serum inhibitors; 4 membrane inhibitors; and 6 complement receptors on the cellular membrane.
北村, 肇, Kitamura, Hajime
core  

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