Results 111 to 120 of about 838,377 (285)

Therapeutic effects of carbon monoxide-saturated hemoglobin-loaded oxygen carrier on idiopathic pulmonary fibrosis in mice

open access: yesZhongguo shuxue zazhi
[Objective] To verify the inhibitory effect of a carbon monoxide hemoglobin-based oxygen carrier (CO-HBOC) on the fibrotic process in mice with idiopathic pulmonary fibrosis (IPF), clarify its efficacy difference compared with hemoglobin-based oxygen ...
XU Peichen   +6 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Complement-mediated opsonic activity in normal and infected human cerebrospinal fluid: early response during bacterial meningitis

open access: yes, 1982
A local defense mechanism in bacterial meningitis was evaluated in humans by measuring complement-mediated opsonic activity (CMOA) in normal and infected cerebrospinal fluid (CSF) with a complement-dependent phagocytic bactericidal assay. CMOA was absent
Zwahlen, André   +4 more
core   +1 more source

A Block-theoretic Proof of Burnside's Normal $p$-complement Theorem

open access: yes
In [3, Theorem 6.7B], the authors use the Main Theorems of Brauer to give a proof of Burnside's Normal $p$-complement Theorem. Unfortunately, the proof contains an error. We take this opportunity to give a proof along similar lines, circumventing the error by means of a well-known result on traces of totally positive cyclotomic integers.
openaire   +2 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Biosynthesis of complement C4 messenger RNA in normal human kidney [PDF]

open access: yes, 1989
Feucht, Helmut E.   +6 more
core   +1 more source

The change and clinical significance of the serum uric acid levels in patients with lupus nephritis

open access: yesLinchuang shenzangbing zazhi, 2017
Objective To observe the serum uric acid levels in patients with lupus nephritis(LN)and explore its relationship with renal damage.Methods A retrospective analysis of the data of110 cases for nephrology renal biopsy and diagnosis of LN patients was made ...
WANG Yi-ya, WU Yong-gui
doaj  

Association of C4d with disease activity in anti-neutrophil cytoplasmic antibody-associated vasculitis: evidence for classical/lectin complement pathway activation

open access: yesArthritis Research & Therapy
Background We aimed to investigate the involvement of the classical/lectin complement pathway in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) by exploring the complement activation fragment C4d in association to AAV activity ...
Anna Juto   +8 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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