Results 91 to 100 of about 1,873,770 (160)

Viability Assessment During Normothermic Machine Liver Perfusion: A Literature Review

International audienceThe discrepancy between donor organ availability and demand leads to a significant waiting‐list dropout rate and mortality.
Jeddou, Heithem, Sulpice, Laurent, Samson, Michel, Boudjema, Karim, Tzedakis, Stylianos, Chaouch, Mohamed Ali   +5 more
core   +1 more source

Evaluation of target temperature on effectiveness of myocardial preservation during hypothermic machine perfusion

JHLT Open
Background: Ex-situ heart perfusion (ESHP) has been proposed as an optimal method for preserving donated hearts prior to transplantation. Hypothermic oxygenated perfusion (HOP) is a simple method from a device design perspective, with enhanced safety ...
Guilherme Mainardi Aguiar da Silva, MD, Mitchell J. Wagner, Sanaz Hatami, MD/PhD, Parham Hassanzadeh, Xiuhua Wang, PhD, Benjamin A. Adam, MD, Jayan Nagendran, MD/PhD, Darren H. Freed, MD/PhD   +7 more
doaj   +1 more source

Perfusate Proteins Detected during Normothermic Machine Perfusion of Discarded Human Livers.

, 2019
Perfusate proteins detected during Normothermic Machine Liver Perfusion of discarded human livers using proteomics. A total of 12 livers, grouped according to viability criteria, assessed across timepoints at the start, after 2 hours and the end of ...
Afford, Simon, Stephenson, Barney, Wallace, Lorraine   +2 more
core   +2 more sources

Long-term machine perfusion of human split livers: a new model for regenerative and translational research

Nature Communications
Recent advances in machine perfusion have revolutionised the field of transplantation by prolonging preservation, permitting evaluation of viability prior to implant and rescue of discarded organs.
Ngee-Soon Lau, Geoffrey McCaughan, Mark Ly, Ken Liu, Michael Crawford, Carlo Pulitano   +5 more
doaj   +1 more source

The Risk of Microbial Transmission in Recipients of Donor Livers That Underwent Hypothermic or Normothermic Machine Perfusion

Transplantation Direct
Background. Ex situ machine perfusion is increasingly used to preserve and assess donor livers before transplantation. Compared with traditional static cold storage (SCS), machine perfusion exposes livers to an additional risk of microbial contamination.
Chikako Endo, MD, Bianca Lascaris, MD, Isabel M. A. Brüggenwirth, MD, PhD, Jan Roggeveld, MBO, Hans Blokzijl, MD, PhD, Vincent E. de Meijer, MD, PhD, M. H. Edwina Doting, MD, PhD, Robert J. Porte, MD, PhD   +7 more
doaj   +1 more source

Improving Kidney Transplant Outcomes Using Normothermic Machine Perfusion

A/Pr Natasha RogersKidneys donated for transplantation are at risk of damage that prevent the organ from working and reduce its lifespan. Normothermic machine perfusion is a device that can circulate oxygenated blood at normal body temperature through a ...

core  

The impact of nutritional strategies on renal energy metabolism during normothermic machine perfusion [PDF]

The aim of this thesis was to advance the understanding and preservation of renal energy metabolism through the application of nutritional modifications during ex vivo normothermic machine perfusion (NMP).
van Furth, Lydia Annick; id_orcid
core   +1 more source

Limited Risk of Microbial Contamination During Hypothermic and Normothermic Machine Perfusion of Donor Kidneys [PDF]

Background: Both hypothermic machine perfusion (HMP) and normothermic machine perfusion (NMP) are increasingly used for preservation of deceased donor kidneys.
Minnee, Robert C., Reinders, Marlies E.J., Chong, Ga Lai M., Schurink, Carolina A.M., Slagter, Julia S., Porte, Robert J.   +5 more
core   +1 more source

Advances in Kidney Transplant, Machine Perfusion, and Viability Markers

Kidney and Dialysis
Despite improvements in kidney transplantation rates, the shortage of donor kidneys remains a critical issue, exacerbated by non-utilization of recovered kidneys due to quality concerns, necessitating advancements in perfusion methods to enhance graft ...
Stephanie Y. Ohara, Mariana Chavez-Villa, Shennen Mao, Jacob Clendenon, Julie Heimbach, Randi Ryan, Lavanya Kodali, Michelle C. Nguyen, Rafael Nateras-Nunez, Caroline C. Jadlowiec   +9 more
doaj   +1 more source

Normothermic machine perfusion versus static cold storage for liver transplantation: a systematic review and meta-analysis. [PDF]

Acta Cir Bras
Valente MLS, Magalhães ACPS, Carmo HMOD, Dalto Junior D, Dorea BS, Zamban MM.   +5 more
europepmc   +1 more source