Results 71 to 80 of about 1,873,770 (160)

Machine perfusion for liver transplantation: opportunities and challenges for the next generation of transplant surgeons

Frontiers in Transplantation
Machine perfusion is reshaping liver transplantation by turning preservation from passive storage into an active, physiologic intervention. This review synthesizes randomized and real-world evidence on hypothermic oxygenated and normothermic approaches ...
Cody L. Mullens, Cody L. Mullens, Cody L. Mullens, Kumaran Shanmugarajah, Glenn K. Wakam   +4 more
doaj   +1 more source

Ex-vivo normothermic liver perfusion: an update.

, 2010
PURPOSE OF REVIEW: There is increasing disparity between the supply of acceptable donor organs and the number of potential transplant recipients. The shortage of organs for transplantation demands optimal utilization of a wider spectrum of donor organs ...
Friend, PJ, Vogel, T, Friend, Peter, Brockmann, JG   +3 more
core   +1 more source

Hypothermic Machine Perfusion in Deceased Donor Kidney Transplantation: Provider and Transplant Center Practices and Perspectives

Clinical Transplantation, Volume 40, Issue 8, August 2026.
ABSTRACT Background Hypothermic machine perfusion (HMP), an organ preservation technique used in deceased donor kidney transplantation, improves early outcomes compared to traditional static cold storage while also providing a loosely validated organ viability assessment. Methods We designed a survey to better understand the practices, perceptions, and
Beatrice P. Concepcion, Laura A. Binari, Vasanthi Balaraman, Angie Nishio‐Lucar, Anju Yadav, Ankita Patel, Kenneth J. Woodside, Krista L. Lentine, M. Lee Sanders, Oluwafisayo O. Adebiyi, Sabiha M. Hussain, Shikha Mehta, Vignesh Viswanathan, Xingxing S. Cheng, Ronald F. Parsons   +14 more
wiley   +1 more source

Normothermic Machine Perfusion of Kidneys: Optimization of Perfusate

, 2020
Chronic kidney disease and end-stage renal disease (ESRD) are becoming increasingly prevalent in the world. The World Health Organization estimates that in 2015, 1.2 million people died from kidney failure, an increase of 32% from a decade ago.
Wu, Yilun
core   +1 more source

Criteria to Assess Bile Production after 2.5 hours of Normothermic Machine Perfusion.

, 2014
Criteria are: 1) Cumulative bile production of ≥10 grams after 2.5 h and 2) a bile production of ≥4 grams in the preceding hour (1.5–2.5 h of perfusion).Criteria to Assess Bile Production after 2.5 hours of Normothermic Machine Perfusion.
Negin Karimian (523239), Sanna op den Dries (523237), Henri G. D. Leuvenink (167159), Pepijn D. Weeder (654589), Annette S. H. Gouw (523242), Ton Lisman (46337), Robert J. Porte (447490), Marieke T. de Boer (523240), Michael E. Sutton (523238), Janneke Wiersema-Buist (523241)   +9 more
core   +1 more source

Criteria for viability assessment of discarded human donor livers during ex vivo normothermic machine perfusion.

PLoS ONE, 2014
Although normothermic machine perfusion of donor livers may allow assessment of graft viability prior to transplantation, there are currently no data on what would be a good parameter of graft viability. To determine whether bile production is a suitable
Michael E Sutton, Sanna op den Dries, Negin Karimian, Pepijn D Weeder, Marieke T de Boer, Janneke Wiersema-Buist, Annette S H Gouw, Henri G D Leuvenink, Ton Lisman, Robert J Porte   +9 more
doaj   +1 more source

Metabolic and lipidomic profiling of steatotic human livers during ex situ normothermic machine perfusion guides resuscitation strategies.

PLoS ONE, 2020
There continues to be a significant shortage of donor livers for transplantation. One impediment is the discard rate of fatty, or steatotic, livers because of their poor post-transplant function.
Siavash Raigani, Negin Karimian, Viola Huang, Anna M Zhang, Irene Beijert, Sharon Geerts, Sonal Nagpal, Ehab O A Hafiz, Fermin M Fontan, Mohamed M Aburawi, Paria Mahboub, James F Markmann, Robert J Porte, Korkut Uygun, Martin Yarmush, Heidi Yeh   +15 more
doaj   +1 more source

Risk factors of delayed kidney graft function following donation after circulatory death – a retrospective cohort study of Swiss kidney transplants

Swiss Medical Weekly
AIMS OF THE STUDY: On 1 September 2011, donation after circulatory death (DCD) organ donation resumed in Switzerland after the DCD programme had been suspended for four years due to jurisdictional and medico-ethical discrepancies.
Maurice Bischof, Simon Schwab, Julius Weiss, Franziska Beyeler, Christian Brunner, Sabine Camenisch, Raphaël Giraud, Yvonne Hilpertshauser, Matthias Peter Hilty, Marco Rusca, Kai Tisljar, Thomas Müller, Franz Immer   +12 more
doaj   +1 more source

The Applications and Future Prospects of Organ Medicine

Health Care Science, Volume 5, Issue 4, Page 261-265, August 2026.
Jiayi Zhang, Youlu Liu, Yuexin Li, Rican Hu, Runbing Mo, Yuyi Zhang, Guangliang Huang, Xiaoshun He   +7 more
wiley   +1 more source

Long-term normothermic machine perfusion of the liver:a world of opportunities [PDF]

Liver transplantation is the only curative treatment option for end-stage liver disease. Transplantation requires donor livers, which are scarce. The global shortage of donor organs, coupled with the increasing demand for liver transplantation, has led ...
Lascaris, Bianca; id_orcid
core   +1 more source