Results 51 to 60 of about 1,873,770 (160)

Biochemical Composition of Perfusion Fluid Used For Normothermic Machine Perfusion of Donor Livers.

, 2014
* To convert values for glucose to mg/dL, multiply by 18.02. To convert values for lactate to mg/dL, multiply by 9.01. To convert values for hemoglobin to g/dL, multiply by 1.650.
Negin Karimian (523239), Sanna op den Dries (523237), Henri G. D. Leuvenink (167159), Pepijn D. Weeder (654589), Annette S. H. Gouw (523242), Ton Lisman (46337), Robert J. Porte (447490), Marieke T. de Boer (523240), Michael E. Sutton (523238), Janneke Wiersema-Buist (523241)   +9 more
core   +1 more source

Defatting of donor transplant livers during normothermic perfusion and modulating extended-criteria donor graft tolerance to ischaemia-reperfusion injury [PDF]

The limited availability of suitable donor livers remains a critical challenge in liver transplantation, necessitating the use of extended criteria donor (ECD) livers, including those from donation after circulatory death (DCD) donors and those ...
Abbas, Syed Hussain
core   +1 more source

Impact of Machine Perfusion on the Immune Response After Liver Transplantation – A Primary Treatment or Just a Delivery Tool

Frontiers in Immunology, 2022
The frequent use of marginal livers forces transplant centres to explore novel technologies to improve organ quality and outcomes after implantation.
Rebecca Panconesi, Rebecca Panconesi, Mauricio Flores Carvalho, Daniele Dondossola, Paolo Muiesan, Paolo Muiesan, Philipp Dutkowski, Andrea Schlegel, Andrea Schlegel, Andrea Schlegel   +9 more
doaj   +1 more source

The Anti‐Inflammatory Effect of Normothermic Machine Perfused Human Kidneys on Monocyte‐Derived Dendritic Cells

Artificial Organs, EarlyView.
The immunogenicity of donor kidneys on NMP can be studied using monocyte‐derived dendritic cells. Incubation with perfusate showed an anti‐inflammatory dendritic cell phenotype and function that suggests the release of an anti‐inflammatory factor or factors during NMP. ABSTRACT Background The immunomodulatory activity of normothermic machine perfusion (
Laura W. D. Knijff, Asel S. Arykbaeva, Sandra W. van der Kooij, Dorottya K. de Vries, Mieke F. van Essen, Ian P. J. Alwayn, Henri G. D. Leuvenink, Rutger J. Ploeg, Cees van Kooten   +8 more
wiley   +1 more source

No Kidney Left Behind: Rescuing Unused Donor Kidneys for Transplant at the First Centralized Assessment and Repair Center

Transplant International
Rescue of non-used kidneys may be facilitated using sub-normothermic acellular machine perfusion (SNAP), which can prolong safe preservation times and provide additional viability assessment.
Christopher L. Jaynes, Christopher L. Jaynes, William C. Goggins, Matthew L. Holzner, Jacqueline Garonzik-Wang, Henri G. D. Leuvenink, Henri G. D. Leuvenink   +6 more
doaj   +1 more source

Heart Donation After Controlled Circulatory Death in Noncardiac Surgery Hospitals With a Mobile Heart Team: A Case Series From an Italian Regional Program and Integrated Review of the Literature

Artificial Organs, EarlyView.
In this series of 19 DCD donors using TA‐NRP, 89.5% of hearts were successfully transplanted with no PGD, no postoperative ECMO, and no 30‐day mortality, demonstrating the feasibility and safety of this approach. ABSTRACT Controlled donation after circulatory death (cDCD) with thoracoabdominal normothermic regional perfusion (TA‐NRP) has emerged ...
Maria Benedetto, Valentina Roncarati, Arianna Campana, Erika Cordella, Domenico Nocera, Sofia Martin‐Suarez, Luca Botta, Davide Pacini, Letizia Perinati, Massimo Baiocchi, Tommaso Tonetti, Fabrizio Monaco   +11 more
wiley   +1 more source

Use of Intralipid Therapy and Therapeutic Plasma Exchange in the Management of Cholecalciferol Rodenticide Exposure in a Dog: A Case Report

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To describe the presentation and outcome of a case of suspected cholecalciferol rodenticide intoxication managed with both intralipid emulsion (ILE) and therapeutic plasma exchange (TPE). Case Summary A 3‐year‐old, neutered female, crossbreed dog presented for acute‐onset vomiting and lethargy after suspected exposure to ...
Tanvi A. Kamat, Kara D. Altman, Emma Donnelly, Neus Elias Santo‐Domingo   +3 more
wiley   +1 more source

Real-time monitoring of mitochondrial oxygenation during machine perfusion using resonance Raman spectroscopy predicts organ function

Scientific Reports
Organ transplantation is a life-saving procedure affecting over 100,000 people on the transplant waitlist. Ischemia reperfusion injury (IRI) is a major challenge in the field as it can cause post-transplantation complications and limit the use of organs ...
Rohil Jain, Emmanuella O. Ajenu, Manuela Lopera Higuita, Ehab O. A. Hafiz, Alona Muzikansky, Padraic Romfh, Shannon N. Tessier   +6 more
doaj   +1 more source

Surgical technique of donation after circulatory death heart procurement using direct procurement and hypothermic oxygenated perfusion preservation

JHLT Open
Introduction: Donation after circulatory death (DCD) has re-emerged as a means of expanding the donor heart pool. Current clinical practice relies mainly on direct procurement followed by normothermic machine perfusion or on thoraco-abdominal ...
K. Vandendriessche, J. Brouckaert, K. Van de Voorde, F. Gaublomme, K. Degezelle, J. Van Cleemput, A. Wallinder, F. Rega   +7 more
doaj   +1 more source

An adaptable research platform for ex vivo normothermic machine perfusion of the liver [PDF]

, 2023
PURPOSE: This paper presents an assessment of a low-cost organ perfusion machine designed for use in research settings. The machine is modular and versatile in nature, built on a robotic operating system (ROS2) pipeline allowing for the addition of ...
Lindenroth, L, Davidson, BR, Rai, ZL, Gander, A, Magbagbeola, M, Dwyer, G, Stilli, A, Stoyanov, D, Doyle, K   +8 more
core   +1 more source