Results 11 to 20 of about 296,712 (303)
The interaction of Notch signalling, haemodynamic flow and angiogenesis in Von Hippel-Lindau mutant zebrafish. [PDF]
Introduction: There is increasing evidence that the endothelium is able to transduce circulatory force into signals which influence angiogenic behaviour.
Watson, Oliver
core +6 more sources
Background: Novel coronavirus disease-2019 (COVID-19) has become a public emergency that is characterized by a dysregulated immune response and hypercoagulable state.
Dilay Karabulut +6 more
doaj +1 more source
Complete understanding of the local stress triaxiality and stress concentration is essential to ensuring structural safety of several structures. A combination of mechanical tests with numerical simulations can be used to obtain this information. One way
Letícia dos Santos Pereira +2 more
doaj +1 more source
On the Reduction of Stress Concentration Factor Around a Notch Using a Functionally Graded Layer [PDF]
The aim of this paper is to study the effect of functionally graded material (FGM) layer around a notch in a plate in three dimensions. Using exponential law of variation of Young's modulus and a coefficient of Poisson constant, the stress concentration ...
Sadek Gouasmi +4 more
doaj +2 more sources
Osteohematology: To be or Notch to be
AbstractOsteohematology is an emerging research field that studies the crosstalk between hematopoietic and bone stromal cells, to elucidate the mechanisms of hematological and skeletal malignancies and diseases. The Notch is an evolutionary conserved developmental signaling pathway, with critical roles in embryonic development by controlling cell ...
Emel Rothzerg +4 more
openaire +2 more sources
In contrast to mammals, the adult zebrafish brain shows neurogenic activity in a multitude of niches present in almost all brain subdivisions.
Nicolas Diotel +3 more
doaj +1 more source
Tetraspanin18 regulates angiogenesis through VEGFR2 and Notch pathways
The VEGF pathway is critically required for vasculogenesis, the formation of the primary vascular network. It is also required for angiogenesis resulting in sprouting and pruning of vessels to generate mature arborizing structures.
Grace X. Li +7 more
doaj +1 more source
Vital registration systems (VRS) are important in the collection of routine data on indicators of development. These are particularly useful if they are properly built to address weaknesses in the system leading to poor data quality.
Julius N. Fobil +4 more
doaj +1 more source
Targeting the Notch Signaling Pathway in Chronic Inflammatory Diseases
The Notch signaling pathway regulates developmental cell-fate decisions and has recently also been linked to inflammatory diseases. Although therapies targeting Notch signaling in inflammation in theory are attractive, their design and implementation ...
Panagiotis F. Christopoulos +8 more
doaj +1 more source
Notch activates Wnt-4 signalling to control medio-lateral patterning of the pronephros [PDF]
Previous studies have highlighted a role for the Notch signalling pathway during pronephrogenesis in the amphibian Xenopus laevis, and in nephron development in the mammalian metanephros, yet a mechanism for this function remains elusive.
Richard W. Naylor +7 more
core +1 more source

