Results 21 to 30 of about 566,967 (348)
Frontiers in Immunology, 2020 Extracellular vesicles (EVs) from adipose tissue-derived stem cells have been reported to attenuate lipopolysaccharide (LPS) induced inflammation and sepsis while the specific mechanism is unclear.
Xiaozhi Bai +8 more
doaj +1 more source
Modeling Podocyte Ontogeny and Podocytopathies with the Zebrafish
Journal of Developmental Biology, 2023 Podocytes are exquisitely fashioned kidney cells that serve an essential role in the process of blood filtration. Congenital malformation or damage to podocytes has dire consequences and initiates a cascade of pathological changes leading to renal ...
Bridgette E. Drummond +2 more
doaj +1 more source
The cargo protein MAP17 (PDZK1IP1) regulates the cancer stem cell pool activating the Notch pathway by abducting NUMB [PDF]
, 2017 Purpose: Cancer stem cells (CSC) are self-renewing tumor cells, with the ability to generate diverse differentiated tumor cell subpopulations. They differ from normal stem cells in the deregulation of the mechanisms that normally control stem cell ...
Carnero Moya, Amancio +4 more
core +1 more source
Mir-34a-5p Mediates Cross-Talk between M2 Muscarinic Receptors and Notch-1/EGFR Pathways in U87MG Glioblastoma Cells: Implication in Cell Proliferation [PDF]
, 2018 Glioblastoma (GBM) is the most aggressive human brain tumor. The high growth potential and decreased susceptibility to apoptosis of the glioma cells is mainly dependent on genetic amplifications or mutations of oncogenic or pro-apoptotic genes ...
Bevilacqua, Valeria +8 more
core +2 more sources
Journal of Pediatric Orthopaedics B, 1997 Ultrasound images of dysplastic and/or unstable hips often display an indentation or notch at the superolateral part of the acetabulum where the iliac wing joins the acetabular roof. We reviewed the ultrasound and subsequent radiographic examinations of 295 babies examined in our hip screening clinic.
N.M. Portinaro, D. Murray, M. K. Benson
openaire +3 more sources
Tunable n-path notch filters for blocker suppression: modeling and verification [PDF]
, 2013 N-path switched-RC circuits can realize filters with very high linearity and compression point while they are tunable by a clock frequency. In this paper, both differential and single-ended N-path notch filters are modeled and analyzed.
Ghaffari, A. +2 more
core +2 more sources
The developmental origins of Notch-driven intrahepatic bile duct disorders
Disease Models & Mechanisms, 2021 The Notch signaling pathway is an evolutionarily conserved mechanism of cell–cell communication that mediates cellular proliferation, cell fate specification, and maintenance of stem and progenitor cell populations. In the vertebrate liver, an absence of
Anabel Martinez Lyons, Luke Boulter
doaj +1 more source
Notch/Delta signaling constrains reengineering of pro-T cells by PU.1 [PDF]
, 2006 PU.1 is essential for early stages of mouse T cell development but antagonizes it if expressed constitutively. Two separable mechanisms are involved: attenuation and diversion. Dysregulated PU.1 expression inhibits pro-T cell survival, proliferation, and
Adams, Stephanie L. +8 more
core +3 more sources
Microorganisms, 2020 Despite the extensive research on Notch signaling involvement in inflammation, its specific role in macrophage response in autoimmune disease and defense mechanisms against bacterial infection, such as Mycobacterium avium paratuberculosis (MAP), remains ...
Esra’a Keewan, Saleh A. Naser
doaj +1 more source
Fatigue Behaviour of Aluminium Members with Different Notch Root Shapes
Buildings, 2022 In unitised curtain walls, the transfer of horizontal loads, mainly wind loads, from the upper into the lower unit is achieved through the head/notch interlocking connection.
Nebojša Buljan +3 more
doaj +1 more source