Results 1 to 10 of about 15,431 (206)

Supplementary Figure 3 from NOTCH3 Signaling Pathway Plays Crucial Roles in the Proliferation of ErbB2-Negative Human Breast Cancer Cells

, 2023
Noritaka Yamaguchi, Tetsunari Oyama, Emi Ito, Hitoshi Satoh, Sakura Azuma, Mitsuhiro Hayashi, Ken Shimizu, Reiko Honma, Yuka Yanagisawa, Akira Nishikawa, Mika Kawamura, Jun‐ichi Imai, Susumu Ohwada, Kuniaki Tatsuta, Jun-ichiro Inoue, Kentaro Semba, Shinya Watanabe   +16 more
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Prominent juxtacortical white matter lesion hallmarks NOTCH3-related intracerebral haemorrhage

Stroke and Vascular Neurology
Background and purpose NOTCH3 p.R544C mutation accounts for 5% of spontaneous intracerebral haemorrhage (ICH) in East Asian patients. We investigated whether certain CT features are associated with NOTCH3-related ICH.Methods Patients with spontaneous ICH
Sung-Chun Tang, Jiann-Shing Jeng, Chih-Hao Chen, Yu-Wen Cheng, Ya-Fang Chen, Hao-Chia Hsu   +5 more
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N3ICD with the transmembrane domain can effectively inhibit EMT by correcting the position of tight/adherens junctions

Cell Adhesion & Migration, 2019
EMT allows a polarized epithelium to lose epithelial integrity and acquire mesenchymal characteristics. Previously, we found that overexpression of the intracellular domain of Notch3 (N3ICD) can inhibit EMT in breast cancer cells. In this study, we aimed
Junyu Tan, Xixun Zhang, Wenjun Xiao, Xiong Liu, Chun Li, Yuxian Guo, Wei Xiong, Yaochen Li   +7 more
doaj   +1 more source

Supplementary Tables 1-4 from Defining NOTCH3 Target Genes in Ovarian Cancer [PDF]

, 2023
Xu Chen, Michelle M. Thiaville, Li Chen, Alexander Stoeck, Jianhua Xuan, Min Gao, Ie−Ming Shih, Tian‐Li Wang   +7 more
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Clinical presentation of Y189C mutation of the NOTCH3 gene in the Polish family with CADASIL

Folia Neuropathologica, 2020
Jolanta Dorszewska, Marta Kowalska, Tomasz Grzegorski, Dorota Dziewulska, Katarzyna Karmelita-Katulska, Anna-Maria Barciszewska, Michał Prendecki, Wojciech Gorczyński, Wojciech Kozubski   +8 more
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Supplementary Legends from A NOTCH3 Transcriptional Module Induces Cell Motility in Neuroblastoma

, 2023
Johan van Nes, Alvin Chan, Tim van Groningen, Peter van Sluis, Jan Köster, Rogier Versteeg   +5 more
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Broad phenotype of cysteine-altering NOTCH3 variants in UK Biobank [PDF]

, 2020
Julie W. Rutten, Remco J. Hack, Marco Duering, Gido Gravesteijn, Johannes G. Dauwerse, Maurice Overzier, Erik B. van den Akker, P. Eline Slagboom, Henne Holstege, Kwangsik Nho, Andrew J. Saykin, Martin Dichgans, Rainer Malik, Saskia A.J. Lesnik Oberstein   +13 more
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Molecular Chaperone BRICHOS Inhibits CADASIL-Mutated NOTCH3 Aggregation In Vitro [PDF]

, 2022
Daniel V. Oliveira, Julia Svensson, Xueying Zhong, Henrik Biverstål, Gefei Chen, Helena Karlström   +5 more
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Histone Modifications Drive Aberrant Notch3 Expression/Activity and Growth in T-ALL

Frontiers in Oncology, 2019
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive blood cancer caused by the deregulation of key T-cell developmental pathways, including Notch signaling.
Luca Tottone, Nadezda Zhdanovskaya, Álvaro Carmona Pestaña, Michele Zampieri, Fabrizio Simeoni, Sara Lazzari, Valeria Ruocco, Maria Pelullo, Paola Caiafa, Maria Pia Felli, Saula Checquolo, Diana Bellavia, Claudio Talora, Isabella Screpanti, Rocco Palermo   +14 more
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Notch3 negatively regulates chemoresistance in breast cancers

Tumor Biology, 2016
To define the role of the NOTCH signaling pathway in the development of chemoresistance and the associated epithelial-mesenchymal transition (EMT), we investigated the effect of Notch3 on adriamycin (ADM)-resistant human breast cancer cells (MCF-7/ADM cells). We found that Notch3 was downregulated and involved in the chemoresistance of MCF-7/ADM cells,
Xiaoting Gu, Chunxiao Lu, Dongxu He, Yangfan Lu, Jian Jin, Dequan Liu, Xin Ma   +6 more
openaire   +2 more sources