Results 251 to 260 of about 103,072 (297)

Notch signaling-targeted biomimetic hydrogel constructs an anti-inflammatory "flood-control" system to alleviate pyroptosis for intervertebral disc degeneration treatment. [PDF]

Mater Today Bio
Zhang R, Zhang X, Guo J, Yang Y, Niu J, Shen H, Zheng Y, Wang J, Wang S, Ni L, Yang H, Shi Q.   +11 more
europepmc   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

Biological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido, Marc Yeste, Yentel Mateo‐Otero   +2 more
wiley   +1 more source

Notch signaling in liver diseases: mechanistic insights and therapeutic implications. [PDF]

Front Cell Dev Biol
Shi Q, Lou N, Huang D, Fu L.
europepmc   +1 more source

Harnessing Generative AI for Sustainable Supply Chains: Lean, Circular and Green Perspectives

Business Strategy and the Environment, EarlyView.
ABSTRACT Generative artificial intelligence is playing a significant role in the transformation of digital ecosystems by reinventing the processes of content generation, process automation, product innovation and customer experience. At the same time that these technologies are becoming more integrated into routine operations, the focus has shifted to ...
Ashutosh Singh, Rsha Alghafes, Judit Petra Koltai, Sushant Kumar Vishnoi   +3 more
wiley   +1 more source

From Material Tensions to Organizational Paradoxes: How Manufacturers Cope With the Limits of Circular Product Design

Business Strategy and the Environment, EarlyView.
ABSTRACT Circular product design (CPD) is central to advancing the circular economy by enabling the narrowing, slowing, and closing of resource flows. Yet, its implementation remains persistently challenging for firms. Prior research has largely framed these challenges as discrete barriers, overlooking the structural contradictions embedded in CPD ...
Vanessa Robertson, Nelly Rahimy, Suleika Bort   +2 more
wiley   +1 more source

Towards precision medicine for brain arteriovenous malformations. [PDF]

J Clin Invest
Hale AT, Kundishora AJ, Kalailingam P, Barak T, Duy PQ, Ramundo CM, Fan B, Li Q, Brastianos PK, Shankar GM, Alper SL, Kleinstiver BP, Musolino PL, Kahle KT.   +13 more
europepmc   +1 more source

Educating agents of change: Investigating curricula to foster sustainability competencies in university

The Curriculum Journal, EarlyView.
Abstract This study critically evaluates the implementation of sustainability competencies in the university‐wide curriculum reform at a Nordic research‐intensive multidisciplinary university. The focus is on assessing how sustainability competencies—especially the newly introduced systems thinking, strategic thinking and futures thinking—are ...
I. Södervik, T. Tuononen, R. Ratvio, T. Laisi, J. Pietikäinen   +4 more
wiley   +1 more source

Silicone oil–based ferrofluid microrobots for versatile magnetic digital microfluidics

Droplet, EarlyView.
A magneto‐silicobotic system is a magnetic digital microfluidic platform that employs a silicone oil–based ferrofluid droplet as a chemically and biologically inert microrobot for the versatile manipulation of droplets and solid particles. Abstract Magnetic digital microfluidics offers a promising alternative to the dominant electrowetting‐based ...
Pu Liu, Leilei Chen, Yulei Fu, Wendong Wang   +3 more
wiley   +1 more source

Targeting Glioblastoma Stem Cells: Therapeutic Strategies and Clinical Perspectives. [PDF]

Cancers (Basel)
Rachamala HR, Lourembam SD, Mukhopadhyay D, Angom RS.   +3 more
europepmc   +1 more source