Results 51 to 60 of about 4,292 (162)
Contact, 2023 We have previously shown that in the developing trunk of zebrafish embryos, two-pore channel type 2 (TPC2)-mediated Ca 2+ release from endolysosomes plays a role in the formation of the skeletal slow muscle.
Keira L. Rice +4 more
doaj +1 more source
Zebrafish inversin mutants develop scoliosis in the absence of laterality defects
Developmental Dynamics, EarlyView.Abstract Background Human mutations in INVERSIN are associated with nephronophthisis, variable penetrance of situs inversus and congenital heart disease. Inversin has been shown to localize to cilia and many of the patient phenotypes are attributed to disrupted cilia function.
Christopher J. Derrick +3 more
wiley +1 more source
The Enigmatic Reissner’s Fiber and the Origin of Chordates
Frontiers in Neuroanatomy, 2021 Reissner’s fiber (RF) is a secreted filament that floats in the neural canal of chordates. Since its discovery in 1860, there has been no agreement on its primary function, and its strong conservation across chordate species has remained a mystery for ...
Francisco Aboitiz +2 more
doaj +1 more source
Zebrafish ventral gastrula fate map reveals neural crest progenitor domain
Developmental Dynamics, EarlyView.Abstract Background Fate maps relate progenitor cell positions to later fates and locations of their progeny, revealing early embryonic organization. Previous zebrafish fate maps identified the origin of germ layers and derivative cell fates, but ventral gastrula progenitor domains were not fully resolved. In particular, the neural crest, a multipotent
Elaine E. Kushkowski, Victoria E. Prince
wiley +1 more source
Food Safety and Health, EarlyView.Punicic acid (PA) was enriched and purified from PSO by molecular distillation with significant anti‐inflammatory activity to RAW264.7 cells, as well as to zebrafish. Anti‐inflammatory mechanism involved regulating NF‐κB and MAPK signaling pathways. ABSTRACT Punicic acid (PA) is the main fatty acid in pomegranate seeds, which shows multiple biological ...
Mengqi Zhang +8 more
wiley +1 more source
eLife, 2018 Segmentation of the axial skeleton in amniotes depends on the segmentation clock, which patterns the paraxial mesoderm and the sclerotome. While the segmentation clock clearly operates in teleosts, the role of the sclerotome in establishing the axial ...
Laura Lleras Forero +10 more
doaj +1 more source
Programmed Cell Senescence in the Mouse Developing Spinal Cord and Notochord
Frontiers in Cell and Developmental Biology, 2021 Programmed cell senescence is a cellular process that seems to contribute to embryo development, in addition to cell proliferation, migration, differentiation and programmed cell death, and has been observed in evolutionary distant organisms such as ...
Jorge Antolio Domínguez-Bautista +2 more
doaj +1 more source
Translating Riedl: The Circulation and Operationalisation of Evolutionary Ideas
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.Rupert Riedl's Order in Living Organisms proposed a systems theory of evolution decades before the concepts it pioneered—homology, burden, the imitative epigenotype—reached the agenda of evolutionary biology. This paper reconstructs the lineages that operationalized his insights across several fields and explores the internal and external reasons for ...
Laura Nuño de la Rosa
wiley +1 more source
Notochord Patterning of the Endoderm
Developmental Biology, 2001 Endodermally derived organs of the gastrointestinal and respiratory system form at distinct anterioposterior and dorsoventral locations along the vertebrate body axis. This stereotyped program of organ formation depends on the correct patterning of the endodermal epithelium so that organ differentiation and morphogenesis occur at appropriate positions ...
Cleaver, Ondine, Krieg, Paul A
openaire +2 more sources
The ancient, segmented, active and permanent notochord
, 2021 The discovery of the notochord as a feature uniting all chordates arose from comparative embryological studies in the 19th century. This discovery established cephalochordates, ascidians (tunicates) and vertebrates as chordates.
Hall, Brian K., Witten, Paul Eckhard
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