Results 31 to 40 of about 4,292 (162)
Biological Research, 2023 Background The biological tube is a basal biology structure distributed in all multicellular animals, from worms to humans, and has diverse biological functions. Formation of tubular system is crucial for embryogenesis and adult metabolism.
Xiuke Ouyang +3 more
doaj +1 more source
ELMOD3-Rab1A-Flotillin2 cascade regulates lumen formation via vesicle trafficking in Ciona notochord
Open Biology, 2023 Lumen development is a crucial phase in tubulogenesis, although its molecular mechanisms are largely unknown. In this study, we discovered an ELMO domain-containing 3 (ELMOD3), which belongs to ADP-ribosylation factor GTPase-activating protein family ...
Amei Liu +3 more
doaj +1 more source
Shaping the zebrafish notochord [PDF]
Development, 2003 Promptly after the notochord domain is specified in the vertebrate dorsal mesoderm, it undergoes dramatic morphogenesis. Beginning during gastrulation,convergence and extension movements change a squat cellular array into a narrow, elongated one that defines the primary axis of the embryo.
Nathalia S, Glickman +3 more
openaire +2 more sources
Neuronal induction and regional identity by co-culture of adherent human embryonic stem cells with chicken notochords and somites [PDF]
The role of somites and notochords in neuroectoderm differentiation from the embryonic ectoderm and its subsequent patterning into regional compartments along rostro-caudal and dorso-ventral axes, especially in humans, remains elusive.
سقا, محسن +7 more
core +1 more source
The cellular and molecular mechanisms of the notochord tubulogenesis in the marine invertebrate Ciona intestinalis [PDF]
, 2013 The biological tube is the fundamental structural design of most internal organs and body systems. Tubulogenesis involves a series of coordinated cellular processes, failure of any of which can cause severe dysfunctions in the organism.
Deng, Wei
core +1 more source
A rare case of chordoma presenting as a Pancoast tumor
Rare Tumors, 2021 The notochord is the defining structure of all chordate embryos. It is a midline structure ventral to the ectoderm, neural plates, and neural arch. Remnants of the notochord ultimately give rise to the nucleus pulposus.
Philip T Sobash +5 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Intervertebral disc degeneration (IDD) is driven by ferroptosis of nucleus pulposus cells (NPCs) as a core pathological mechanism. Nucleus pulposus progenitor cells (NPPCs), exhibiting stem cell‐like properties, yield extracellular vesicles (PEVs) with high affinity for NPCs and enable targeted phenotypic regulation.
Jing Yan +10 more
wiley +1 more source
Analysis of genes controlling notochord development in zebrafish. [PDF]
, 2006 The notochord is a vital and defining organ in vertebrates. Mutagenesis screening in zebrafish identified seven 'dwarf mutants that lack notochord development grumpy, sleepy, bashful, dopey, happy, sneezy and doc.
Thomas, K.A.
core
From notochord to vertebral column: studies on Atlantic salmon (Salmo salar L.) [PDF]
, 2007 The notochord initially form a single-cell file stage of chordoblasts covered by a three layered sheath comprising a basal lamina, a main collagenous layer and an external elastic membrane.
Nordvik, Kari
core +1 more source
Notochord morphogenesis as a mechanical driver of embryo axis elongation [PDF]
, 2021 Early on in development, embryos undergo a dramatic change in shape in order to transform from a collection of cells into a functioning organism with a specialised body morphology.
core +2 more sources