Results 111 to 120 of about 791,967 (356)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Safety of glucosyl hesperidin as a Novel food pursuant to Regulation (EU) 2015/2283

Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on glucosyl hesperidin (GH) as a novel food (NF) pursuant to Regulation (EU) 2015/2283.
EFSA Panel Nutr Novel Foods & Food Allergens NDA
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Comparing Extraction Techniques and Varieties in Grape Stems: A Chemical Assessment of Antioxidant Phenolics

Applied Sciences
Grape stems are undervalued winemaking by-products that constitute a promising source of bioactive phenolics with notable antioxidant potential and diverse industrial applications, including food preservation, cosmetics, and pharmaceuticals.
Gloria Domínguez-Rodríguez, Juan Antonio Nieto, Susana Santoyo, Laura Jaime   +3 more
doaj   +1 more source

Electrospun Oxygen Scavenging Films of Poly(3-hydroxybutyrate) Containing Palladium Nanoparticles for Active Packaging Applications

Nanomaterials, 2018
This paper reports on the development and characterization of oxygen scavenging films made of poly(3-hydroxybutyrate) (PHB) containing palladium nanoparticles (PdNPs) prepared by electrospinning followed by annealing treatment at 160 °C.
Adriane Cherpinski, Melike Gozutok, Hilal Turkoglu Sasmazel, Sergio Torres-Giner, Jose M. Lagaron   +4 more
doaj   +1 more source

Safety of hot water extract of fruits and peduncles of Hovenia dulcis as a novel food pursuant to Regulation 1(EU) 2015/2283 [PDF]

, 2020
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the safety of 'Hovenia dulcis fruit extract' as a novel food (NF) for its use in food supplements.
Turck, Dominique, Heinonen, Marina, EFSA Panel Nutr Novel Foods Food A   +2 more
core   +1 more source

Validation of coffee by-products as novel food ingredients

Innovative Food Science & Emerging Technologies, 2019
This research aimed to validate coffee husk, parchment and silverskin as new health-promoting food ingredients. Characterization of the novel ingredients was carried out by Raman and infrared spectroscopy and analysis of total phenolic compounds ...
Amaia Iriondo-DeHond, Natalia Aparicio García, Beatriz Fernández-Gómez, Eduardo Guisantes-Batán, Francisco Vélazquez Escobar, G. P. Blanch, M. S. San Andres, S. Sánchez-Fortún, M. D. del Castillo   +8 more
semanticscholar   +1 more source

Novel Food-Based Product Communication: A Neurophysiological Study

Nutrients, 2020
The steady increase in the global food demand requires alternative sources. Food sources from invertebrates could be a viable alternative. Despite a growing interest in terrestrial invertebrates as novel food, Western consumers have to cope with fears ...
Vincenzo Russo, Giulia Songa, L. E. Milani Marin, C. Balzaretti, D. Tedesco   +4 more
semanticscholar   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source