Results 131 to 140 of about 2,044,890 (309)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Designing market-oriented beta-glucan enriched functional foods through conjoint analysis: evidence of differing consumer preferences [PDF]
New product development (NPD) has a significant role to play in the rapidly evolving food supply chain where firms wish to utilise innovative novel ingredients to meet consumers’ increased needs for healthier foods.
Bogue, Joe, Troy, Amy-jane
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Policies supporting organic food and farming in the EU: assessment and development by stakeholders in 11 European countries [PDF]
There is no single 'best way' of policy development. Bottom- up approaches to policy design and a broad debate among stakeholders facilitate policy learning and innovation.
Dabbert, Stephan +3 more
core +1 more source
Improving the quality and safety of organic and low input foods and maximizing the benefits to consumers and producers [PDF]
, 2007 ‘Improving quality and safety and reduction of cost in the European organic and 'low input' supply chains' (QLIF) is an Integrated Project under the 6th Framework Programme of the European Commission which started in March 2004 and will end in February ...
Leifert, Carlo, Niggli, Urs
core
Food, novel foods, and allergenicity
, 2002 Voedselallergie kan gepaard gaan met een groot aantal symptomen (in het maag-darmkanaal, de huid, en de ademhalingsorganen) en kan leiden tot levensbedreigende situaties. De prevalentie van voedselallergie is ongeveer 2% van de bevolking; in kinderen 5-8%.
openaire +2 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Communication system for a tooth-mounted RF sensor used for continuous monitoring of nutrient intake [PDF]
, 2019 In this Thesis, the communication system of a wearable device that monitors the user’s diet is studied. Based in a novel RF metamaterial-based mouth sensor, different decisions have to be made concerning the system’s technologies, such as the power ...
Zufía Mier, Pablo
core +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source