Results 101 to 110 of about 9,104 (252)

Editorial: Prescribing psychotropics: Misuse, abuse, dependence, withdrawal and addiction, Volume II

Frontiers in Psychiatry, 2022
Stefania Chiappini, Stefania Chiappini, Fabrizio Schifano, Giovanni Martinotti, Giovanni Martinotti   +4 more
doaj   +1 more source

Tolazoline, an alpha-adrenergic antagonist, may also block xylazine at off-target sites as inferred from molecular docking

Frontiers in Chemical Biology
Xylazine, a non-opioid α2-adrenoceptor agonist, is increasingly implicated in misuse and opioid-adulterated overdoses. Tolazoline, a non-selective α-adrenergic antagonist, is widely used in veterinary medicine to reverse xylazine-induced sedation and ...
Giuseppe Floresta, Giuseppe Floresta, Vincenzo Patamia, Alberto Granzotto, Alberto Granzotto, Davide Arillotta, Davide Arillotta, Gabriele Duccio Papanti, Gabriele Duccio Papanti, Amira Guirguis, John M. Corkery, Giovanni Martinotti, Giovanni Martinotti, Stefano L. Sensi, Stefano L. Sensi, Stefano L. Sensi, Stefano L. Sensi, Fabrizio Schifano   +17 more
doaj   +1 more source

Reports of Adverse Events Associated with Use of Novel Psychoactive Substances, 2017-2020: A Review. [PDF]

J Anal Toxicol, 2022
Mohr ALA, Logan BK, Fogarty MF, Krotulski AJ, Papsun DM, Kacinko SL, Huestis MA, Ropero-Miller JD.   +7 more
europepmc   +1 more source

Implications of attention‐deficit/hyperactivity disorder diagnostic timing on mental health service utilisation in young adult females: A population‐based record linkage cohort study

JCPP Advances, EarlyView.
Abstract Background Sex differences in the frequency and timing of attention‐deficit/hyperactivity disorder (ADHD) diagnosis exist. While there are multiple known individual and wider consequences for young females with delayed or undiagnosed ADHD, little is known about mental health service utilisation (HSU) impacts.
Estelle Alderson, Nicholas Bowden, Laurie McLay, Ben Beaglehole, Philip J. Schluter   +4 more
wiley   +1 more source

Editorial: Prescribing Psychotropics: Misuse, Abuse, Dependence, Withdrawal and Addiction

Frontiers in Psychiatry, 2021
Stefania Chiappini, Stefania Chiappini, Fabrizio Schifano, Giovanni Martinotti, Giovanni Martinotti   +4 more
doaj   +1 more source

Novel Psychoactive Substances: The Razor's Edge between Therapeutical Potential and Psychoactive Recreational Misuse. [PDF]

Medicines (Basel), 2022
Correia B, Fernandes J, Botica MJ, Ferreira C, Quintas A.   +4 more
europepmc   +1 more source

Alterations in resting‐state functional connectivity relate to psychopathology trajectories during emerging adolescence

JCPP Advances, EarlyView.
Abstract Background A general psychopathology “p‐factor” captures shared variation across psychiatric disorder categories and is associated with dysfunctions in cognitive control. Alterations in resting‐state functional connectivity (RSFC) of cognitive and attentional networks have been associated concurrently with the p‐factor in youth samples ...
Jenna Jones Devine, Garrett R. Hosterman, Jolee Sloss, Adrienne L. Romer   +3 more
wiley   +1 more source

Signal Detection of Depression and Suicidality Associated with Finasteride and Dutasteride: Updated Pharmacovigilance Evidence and Recommendations for Comprehensive Psychiatric Assessment

Brain Sciences
Background/Objectives: Finasteride and dutasteride are 5α-reductase inhibitors that block the conversion of testosterone to dihydrotestosterone, reducing androgenic stimulation of tissues such as the prostate and hair follicles.
Stefania Chiappini, John Martin Corkery, Amira Guirguis, Alessio Mosca, Mya Murray, Davide Arillotta, Luigi Dattoli, Giovanni Martinotti, Stefania Bonaccorso, Fabrizio Schifano, Nicolò Schifano   +10 more
doaj   +1 more source

Knowledge and Use of Novel Psychoactive Substances in an Italian Sample with Substance Use Disorders. [PDF]

Int J Environ Res Public Health, 2022
Dal Farra D, Valdesalici A, Zecchinato G, De Sandre A, Saccon D, Simonato P, Corazza O, Martinotti G, Smith AL, Solmi M.   +9 more
europepmc   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source