Results 141 to 150 of about 4,556,772 (353)

Congenital factor V deficiency in a pediatric patient causing mild hemorrhage

Hematology
Background and Aims This study aimed to elucidate the phenotype and genotype of a patient (9-year-old) with coagulation factor V (FV) deficiency to enhance our understanding of this specific disorder.Methods FV activity and antigen level were evaluated ...
Haiyue Zhang, Jun Wu
doaj   +1 more source

Immunomodulatory Activity In Vitro and In Vivo of a Sulfated Polysaccharide with Novel Structure from the Green Alga Ulvaconglobata Kjellman. [PDF]

Mar Drugs, 2022
Cao S, Yang Y, Liu S, Shao Z, Chu X, Mao W.   +5 more
europepmc   +1 more source

Structure-Based Design of Novel Boronic Acid-Based Inhibitors of Autotaxin [PDF]

, 2011
Harald M. H. G. Albers, Loes J. D. Hendrickx, Rob J. P. van Tol, Jens Hausmann, Anastassis Perrakis, Huib Ovaa   +5 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Formulation of the novel structure curcumin derivative-loaded solid lipid nanoparticles: synthesis, optimization, characterization and anti-tumor activity screening in vitro. [PDF]

Drug Deliv, 2022
Li K, Pi C, Wen J, He Y, Yuan J, Shen H, Zhao W, Zeng M, Song X, Lee RJ, Wei Y, Zhao L.   +11 more
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Screening of antibacterial compounds with novel structure from the FDA approved drugs using machine learning methods. [PDF]

Aging (Albany NY), 2022
Li WX, Tong X, Yang PP, Zheng Y, Liang JH, Li GH, Liu D, Guan DG, Dai SX.   +8 more
europepmc   +1 more source

L-696,474, a novel cytochalasin as an inhibitor of HIV-1 protease. II. Isolation and structure.

, 1992
John G. Ondeyka, Otto D. Hensens, Deborah L. Zink, Richard Ball, R. B. Lingham, Gerald F. Bills, Anne W. Dombrowski, Michael Goetz   +7 more
openalex   +2 more sources

The crystal structure of Li₃(V,P)O₄– a novel potential phase for electrochemical applications [PDF]

, 2013
Ekaterina V. Yakovleva, O. V. Yakubovich, О. В. Димитрова   +2 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source