Results 41 to 50 of about 23,054 (234)
The NADPH Oxidase Nox4 and Aging in the Heart
Aging, 2010 Oxidative stress in mitochondria is believed to promote aging. Although passive leakage of electron from the mitochondrial electron transport chain has been considered as a major source of oxidative stress in the heart and the cardiomyocytes therein, enzymes actively producing reactive oxygen species may also exist in mitochondria.
Tetsuro, Ago +5 more
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Molekulare Mechanismen Proteinkinase C-induzierter Nox4-Hochregulation in humanen Endothelzellen [PDF]
, 2014 Eine verstärkte Transkription von NADPH-Oxidasen (Nox) wird mit der Entstehung von atherosklerotischer Veränderungen in Verbindung gebracht. Die Arbeit unserer Gruppe zeigte, dass die Aktivität der Proteinkinase C (PKC) zu einer Nox4-Hochregulation führt,
Schlufter, Frank Martin
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Tuberculous Fibrosis Enhances Tumorigenic Potential via the NOX4–Autophagy Axis
, 2021 While a higher incidence of lung cancer in subjects with previous tuberculous infection has been reported in epidemiologic data, the mechanism by which previous tuberculosis affects lung cancer remains unclear.
Seong Ji Woo +4 more
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NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma
BMC Cancer, 2021 Background Increased expression of the transcription factor Forkhead box M1 (FOXM1) has been reported to play an important role in the progression and development of multiple tumors, but the molecular mechanisms that regulate FOXM1 expression remain ...
Xiangsheng Su +9 more
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Antioxidants, 2023 Human corneal-endothelial cells (hCEnCs) are located on the inner layer of the cornea. Injury to CEnCs leads to permanent corneal edema, requiring corneal transplantation.
Dae Joong Ma +5 more
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Mediators of Inflammation, 2022 NADPH oxidase 4 (Nox4) is an important source of reactive oxygen species (ROS) production, and its expression is increased in lipopolysaccharide- (LPS-) stimulated lung epithelial cells.
Yueguo Wang +9 more
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A Comparative Analysis of NOX4 Protein Expression in Malignant and Non-Malignant Thyroid Tumors
Current Issues in Molecular Biology, 2023 The comparative analysis of the expression of the reactive oxygen species-generating NADPH oxidase NOX4 from TCGA data shows that the NOX4 transcript is upregulated in papillary thyroid carcinomas (PTC)-BRAFV600E tumors compared to PTC-BRAFwt tumors ...
Salma Fenniche +10 more
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International Journal of General Medicine, 2022 Feng Jiang,1,2 Zhicheng Chen,1,2 Jiemiao Hu,1,2 Qianzhi Liu1,2 1Department of Neurosurgery, Ningbo Hangzhou Bay Hospital, Ningbo, 315336, People’s Republic of China; 2Department of Neurosurgery, Ningbo Branch, Ren Ji Hospital, Shanghai Jiao Tong ...
Jiang F, Chen Z, Hu J, Liu Q
doaj
BIAM switch assay coupled to mass spectrometry identifies novel redox targets of NADPH oxidase 4
Redox Biology, 2019 Aim: NADPH oxidase (Nox) -derived reactive oxygen species have been implicated in redox signaling via cysteine oxidation in target proteins. Although the importance of oxidation of target proteins is well known, the specificity of such events is often ...
Oliver Löwe +6 more
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Tyrosine kinase FYN negatively regulates NOX4 in cardiac remodeling [PDF]
, 2016 NADPH oxidases (Noxes) produce ROS that regulate cell growth and death. NOX4 expression in cardiomyocytes (CMs) plays an important role in cardiac remodeling and injury, but the posttranslational mechanisms that modulate this enzyme are poorly understood.
Kinugawa, Shintaro +25 more
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