Results 111 to 120 of about 7,302 (251)

A Comprehensive Review on Key Chemical Constituents of Indian Pulses and Their Multifaceted Health Benefits in a Global Context

Legume Science, Volume 7, Issue 4, December 2025.
ABSTRACT Pulses are edible seeds of legume plants, but they are distinct from legumes because they are dried seeds before consumption. Because of their economic value and high nutritional content, pulses are integral to diets worldwide. Various pulses such as Macrotyloma uniflorum (horse gram), Glycine max (soybeans), Pisum sativum (field peas), Lens ...
Preeti Semwal, Shankar Gupta, Chahat, Gaurav Joshi, Muhammad Wahajuddin, Bhupinder Kumar   +5 more
wiley   +1 more source

Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk [PDF]

, 2016
Therapeutic interventions that lower LDL-cholesterol effectively reduce the risk of coronary artery disease (CAD). However, statins, the most widely prescribed LDL-cholesterol lowering drugs, increase diabetes risk. We used genome-wide association study (
Asselbergs, Folkert W., Bakker, Paul I. W., Holmes, Michael V., Keating, Brendan J., Moore, Jason H., Palmer, Tom M., Swerdlow, Daniel I., Tragante, Vinicius   +7 more
core   +1 more source

Fenofibrate reduces intestinal cholesterol absorption via PPARα-dependent modulation of NPC1L1 expression in mouse

Journal of Lipid Research, 2007
Fibrates, including fenofibrate, exert their biological effects by binding peroxisome proliferator-activated receptor α (PPARα), a member of the nuclear receptor superfamily of ligand-activated transcription factors.
Mark A. Valasek, Stephen L. Clarke, Joyce J. Repa   +2 more
doaj   +1 more source

Psychiatric genetics and the structure of psychopathology [PDF]

, 2018
For over a century, psychiatric disorders have been defined by expert opinion and clinical observation. The modern DSM has relied on a consensus of experts to define categorical syndromes based on clusters of symptoms and signs, and, to some extent ...
Andreassen, Ole A., Edenberg, Howard J., Faraone, Stephen V., Glatt, Stephen J., Kendler, Kenneth S., Smoller, Jordan W.   +5 more
core   +1 more source

Ezetimibe-sensitive cholesterol uptake by NPC1L1 protein does not require endocytosis

Molecular Biology of the Cell, 2016
Human NPC1L1 protein mediates cholesterol absorption in the intestine and liver and is the target of the drug ezetimibe, which is used to treat hypercholesterolemia. Previous studies concluded that NPC1L1-GFP protein trafficking is regulated by cholesterol binding and that ezetimibe blocks NPC1L1-GFP function by inhibiting its endocytosis.
Johnson, Tory A., Pfeffer, Suzanne R.
openaire   +2 more sources

Diosgenin stimulation of fecal cholesterol excretion in mice is not NPC1L1 dependent

Journal of Lipid Research, 2009
Diosgenin exists in some food supplements and herbal medicines and lowers plasma cholesterol by increasing fecal cholesterol excretion. It is believed that diosgenin promotes fecal cholesterol excretion by stimulating biliary cholesterol secretion and ...
Ryan E. Temel, J. Mark Brown, Yinyan Ma, Weiqing Tang, Lawrence L. Rudel, Yiannis A. Ioannou, Joanna P. Davies, Liqing Yu   +7 more
doaj   +1 more source

Sterol enriched fractions obtained from Agaricus bisporus fruiting bodies and by-products by compressed fluid technologies (PLE and SFE) [PDF]

, 2013
This is the author’s version of a work that was accepted for publication in Innovative Food Science and Emerging Technologies. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other ...
Aldars-García, Laila, Gil-Ramírez, Alicia, Jiverdeanu, Rodica M, Marín, Francisco R., Palanisamy, Marimuthu, Reglero, Guillermo, Ruiz-Rodríguez, Alejandro, Soler-Rivas, Cristina   +7 more
core   +2 more sources

Regulation of intestinal NPC1L1 expression by dietary fish oil and docosahexaenoic acid

Journal of Lipid Research, 2007
To address the effect of the n-3 fatty acid, docosahexaenoic acid (22:6), on proteins that play a role in cholesterol absorption, CaCo-2 cells were incubated with taurocholate micelles alone or micelles containing 22:6 or oleic acid (18:1). Compared with
Satya N. Mathur, Kim R. Watt, F. Jeffrey Field   +2 more
doaj   +1 more source

The Role of Turmeric Powder in Lipid Metabolism and Its Effect on Quality of the First Quail\u27s Egg [PDF]

, 2013
This experiment was conducted to determine the role of turmeric powder in lipid metabolism andits influence on the quality of the first quail\u27s egg. Sixty female quails were assigned into a completelyrandomized design with four treatments (levels of ...
Ekastuti, D. R. (D), Kusumorini, N. (N), Manalu, W. (W), Saraswati, T. R. (T)   +3 more
core  

Pravastatin Modulate Niemann-Pick C1-Like 1 and ATP-Binding Cassette G5 and G8 to Influence Intestinal Cholesterol Absorption

Journal of Pharmacy & Pharmaceutical Sciences, 2015
Purpose. Niemann-Pick C1-like 1 (NPC1L1), ATP-binding cassette (ABC)G5, and ABCG8 mediate intestinal cholesterol absorption. It is unclear whether pravastatin (PR) or ezetimibe (EZ) affect expression of these transporters.
Atsushi Kawase, Seiji Hata, Mai Takagi, Masahiro Iwaki   +3 more
doaj   +1 more source