Results 91 to 100 of about 57,135 (271)

NPY mediates ATP-induced neuroproliferation in adult mouse olfactory epithelium

Neurobiology of Disease, 2010
In the CNS, ATP is released upon injury and promotes neuroproliferation via purinergic receptors. In the olfactory epithelium, ATP promotes the synthesis and release of neurotrophic factor NPY in neonates and induces neuroproliferation in neonatal and ...
Cuihong Jia, Colleen Cosgrove Hegg
doaj   +1 more source

Npy deletion in an alcohol non-preferring rat model elicits differential effects on alcohol consumption and body weight. [PDF]

, 2016
Neuropeptide Y (NPY) is widely expressed in the central nervous system and influences many physiological processes. It is located within the rat quantitative trait locus (QTL) for alcohol preference on chromosome 4.
Bell, Richard L., Cao, Yong, Graves, Tamara, Liang, Tiebing, Lumeng, Lawrence, Qiu, Bin, Stewart, Robert B., Yong, Weidong, Zhang, Lingling   +8 more
core   +1 more source

G Protein–Coupled Receptors in Olfactory Signaling and Related Disorders: Mechanisms and Therapeutic Implications

Sensory Neuroscience, EarlyView.
This schematic highlights GPCRs as the central hub of olfactory signaling in health and disease. The central GPCR shows odorant activation and downstream pathways. Surrounding quadrants illustrate four GPCR‐mediated themes: odor perception and adaptation, mucosal immunity and regeneration, memory consolidation via neural circuits, and GPCR‐related ...
Zishuo Guo, Hongjie Du, Fanyu Yuan, Yuhan Dong, Fangyuan Zhu, Jian Liu, Chengzhilin Li, Xu Guo, Zhaoze Yang, Wenwen Qi, Ming Xia, Chengcheng Liu   +11 more
wiley   +1 more source

Effect of Resistance Training on Appetite Regulation and Level of Related Peptidesin Sedentary Healthy Men

Medical Laboratory Journal, 2017
Background and Objectives: Resistance training is a key component of exercise recommendations for weight control, yet very little is known about the effects of resistance training on appetite and related peptides.
A Jafari, M Peeri, M Azarbayejani, H Homai   +3 more
doaj  

Central NPY‐Y5 sub‐receptor partially functions as a mediator of NPY‐induced hypothermia and affords thermotolerance in heat‐exposed fasted chicks

Physiological Reports, 2017
Exposure of chicks to a high ambient temperature (HT) has previously been shown to increase neuropeptide Y (NPY) mRNA expression in the brain. Furthermore, it was found that NPY has anti‐stress functions in heat‐exposed fasted chicks.
Hatem M. Eltahan, Mohammad A. Bahry, Hui Yang, Guofeng Han, Linh T. N. Nguyen, Hiromi Ikeda, Mohamed N. Ali, Khairy A. Amber, Mitsuhiro Furuse, Vishwajit S. Chowdhury   +9 more
doaj   +1 more source

Glial-derived neurotrophic factor modulates enteric neuronal survival and proliferation through neuropeptide Y. [PDF]

, 2006
BACKGROUND & AIMS: Glial-derived neurotrophic factor (GDNF) promotes the survival and proliferation of enteric neurons. Neuropeptide Y (NPY) is an important peptide regulating gastrointestinal motility.
Anitha, M., Chandrasekharan, B., Grouzmann, E., Mwangi, S., Salgado, J.R., Sitaraman, S.V., Srinivasan, S.   +6 more
core   +2 more sources

Mycosis Fungoides Is a Proliferation of Multiple Mutational Subclones

The Journal of Dermatology, EarlyView.
ABSTRACT Mycosis fungoides (MF) is a unique type of lymphoma with an excellent prognosis presenting with a wide variety of clinical and histological findings. Recent sophisticated research techniques have revealed that very slow changes in the clinical and histological pictures of one patient over time are due to intratumoral heterogeneity.
Ryoma Honda, Toshihisa Hamada, Makoto Sugaya   +2 more
wiley   +1 more source

Diet transition to a high-fat diet for 3 weeks reduces brain omega-3-fatty acid levels, alters BDNF signaling and induces anxiety & depression-like behavior in adult rats [PDF]

, 2012
Background: The consumption of diets high in calories and low in nutrient value is becoming increasingly common in modern society, which can lead to metabolic disorders like diabetes and obesity, and potentially to psychiatric disorders.
Fernando Gomez-Pinilla, Sandeep Sharma, Yumei Zhuang   +2 more
core   +1 more source

What doesn't kill you makes you stranger: Dipeptidyl peptidase-4 (CD26) proteolysis differentially modulates the activity of many peptide hormones and cytokines generating novel cryptic bioactive ligands [PDF]

, 2019
Dipeptidyl peptidase 4 (DPP4) is an exopeptidase found either on cell surfaces where it is highly regulated in terms of its expression and surface availability (CD26) or in a free/circulating soluble constitutively available and intrinsically active form.
Aguilar-Pérez, Alexandra, Awad, Mohamed E., Eisa, Nada H., Elmansi, Ahmed M., Fulzele, Sadanand, Hamrick, Mark W., Herberg, Samuel, Hill, William D., Hussein, Khaled A., Isales, Carlos M., Kondrikov, Dmitry, McGee-Lawrence, Meghan E., Periyasamy-Thandavan, Sudharsan, Volkman, Brian F.   +13 more
core   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source