Results 111 to 120 of about 33,925 (257)

Regulation of NPY/NPY Y1 receptor/G protein system in rat brain cortex

, 1995
Neuropeptide Y (NPY) content, NPY receptors, and alpha-subunits of the G proteins Go and Gi were determined in cerebral cortex of male normotensive Wistar-Kyoto and spontaneously hypertensive rats at 3-28 wk of age and of adult female rats.
Rascher, W., Bischoff, A., Michel, M. C., Farke, W., Lewejohann, K., Feth, F.   +5 more
core   +2 more sources

Novel Expression Pattern of Neuropeptide Y Immunoreactivity in the Peripheral Nervous System in a Rat Model of Neuropathic Pain

Molecular Pain, 2015
Background Neuropeptide Y (NPY) has been implicated in the modulation of pain. Under normal conditions, NPY is found in interneurons in the dorsal horn of the spinal cord and in sympathetic postganglionic neurons but is absent from the cell bodies of ...
Claire Magnussen, Shih-Ping Hung, Alfredo Ribeiro-da-Silva   +2 more
doaj   +1 more source

Effects of 6‐OHDA‐Mediated Chemical Denervation of Sympathetic Axons in Inguinal Subcutaneous White Adipose Tissue

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims White adipose tissue (WAT) innervation by sensory and sympathetic axons contributes to tissue functions, but the consequences of selectively disrupting sympathetic input to WAT remain incompletely defined. Materials and Methods We utilised 6‐hydroxydopamine (6‐OHDA) as a validated approach to achieve bilateral sympathetic denervation of ...
Gilian Gunsch, Gargi Mishra, Magdalena Blaszkiewicz, Erica de Sousa, Jake W. Willows, Katharine W. Alltop, Annemarie Towle, Shawn Collins, Andre Khalil, Isabel F. Snodgrass, Lara Agha, Kiran Prakash, Rashmika Maganuru, Sugasini Dhavamani, John W. Newman, Kristy L. Townsend   +15 more
wiley   +1 more source

Nitric oxide mediates the neuroproliferative effect of Neuropeptide Y

, 2012
Neuropeptide Y (NPY) is widely expressed in both the central and peripheral nervous system and has an important role in the regulation of adult hippocampal neurogenesis by mediating the proliferation of neural precursor cells in both health and disease ...
Cheung, Angela
core   +1 more source

Novel targets in headache: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This narrative review summarizes novel applications for the use of calcitonin gene‐related peptide (CGRP)‐targeted therapies that go beyond migraine, the latest updates with respect to targeting pituitary adenylate cyclase‐activating peptide (PACAP) as therapeutic in migraine, as well as exploring other more recently ...
Adriana Della Pietra, Peter J. Goadsby, Carolina Oldoni, Stephen Silberstein, Fred Cohen, Simon Akerman   +5 more
wiley   +1 more source

The Expression of Neuropeptides in Pulpitis: A Systematic Review and Meta‐Analysis

International Endodontic Journal, EarlyView.
ABSTRACT Background Neuropeptides play key roles in the inflammatory, nociceptive and reparative processes of the dental pulp. Their upregulation has been frequently observed in inflamed pulps, suggesting potential diagnostic value supporting a role for neurogenic inflammation in symptomatic irreversible pulpitis.
N. Watson, D. Edwards, Q. Vuong, I. Obara   +3 more
wiley   +1 more source

Scalp Dysesthesia: Emerging Pathophysiologic Insights and Therapeutic Implications

International Journal of Dermatology, EarlyView.
Scalp dysesthesia is a chronic condition diagnosed through exclusion. This scoping review synthesized data from 59 patients to identify recurrent clinical features, comorbidities, and management strategies that may support earlier diagnosis. Emerging patterns suggest that neuronal sensitization may underlie common symptoms.
Aditya K. Gupta, Jaspreet Kaur, Amanda Liddy, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

Adaptation to extreme environments: A review of Antarctic fish physiology

Journal of Fish Biology, EarlyView.
Abstract Having evolved in the chronically cold and thermally stable waters of the Southern Ocean (SO) for millions of years, Antarctic fish possess a suite of physiological specializations that enable them to survive at temperatures near the freezing point of seawater. Adaptations include the evolution of antifreeze proteins, modifications of membrane
Seungyeon Lee, Sachithra Amarin Hettiarachchi, Il‐Chan Kim, Jae‐Seong Lee, Thomas Desvignes, Julia M. York, Laura Ghigliotti, Jilda Alicia Caccavo, Jin‐Hyoung Kim   +8 more
wiley   +1 more source

NPY stimulated the proliferation of cultured VSMCs, and the NPY receptors were involved in this process.

, 2015
(A) VSMCs were stimulated by NPY at different concentration for 24 hours. The last column showed 10% serum data (n = 4). (B) VSMCs were pre-incubated with single or combinational NPY receptor antagonists (NPY 1, 2 and 5 receptor antagonists), and then ...
Ying-Xin Qi (282220), Qing-Ping Yao (282224), Xiao-Hu Chen (763764), Li-Zhi Gao (2558455), Ping Zhang (86495), Bao-Rong Shen (282223), Guo-Liang Wang (228171), Yue Han (560788), Zong-Lai Jiang (282226)   +8 more
core   +1 more source

Chicken or egg? The evolutionary riddle of CMS and Rf in plants

Journal of Integrative Plant Biology, EarlyView.
Cytoplasmic male sterility (CMS) reduces pollen fertility and nuclear Rf genes restore fertility. This Commentary explores support for the “arms race” and “pre‐adaptation” models for CMS–Rf co‐evolution. CMS and Rf interact dynamically, influencing plant reproduction, stress tolerance, and hybrid seed production, highlighting co‐evolutionary processes ...
Peilin Wang, Zhe Zhao, Qibin Wu, Yaoguang Liu, Youxiong Que   +4 more
wiley   +1 more source