Results 121 to 130 of about 33,925 (257)

Effects of neuropeptide Y on electrical activity and myocardial contractility

Учёные записки Казанского университета: Серия Естественные науки, 2018
Neuropeptide Y (NPY) and agonist Leu(31)Pro(34)NPY were used to determine the type of NPY receptors involved in electrical activity and myocardial contraction.
A.A. Zverev, T.A. Anikina, N.G. Iskakov, A.V. Krulova, P.M. Masliukov, J.P. Timmermans, T.L. Zefirov   +6 more
doaj  

The reproducibility gap in graph neural network workflows for cell dynamics: A checklist‐driven case study

Journal of Microscopy, EarlyView.
Abstract As part of a Global BioImage Analysts' Society (GloBIAS) initiative, we evaluated the reproducibility of a Graph Neural Network (GNN) study on cell dynamics using structured, community‐developed checklists from the Quality Assessment and Reproducibility for Instruments and Images in Light Microscopy (QUAREP‐LiMi) initiative.
Martin Schätz, Ko Sugawara
wiley   +1 more source

Plasma neuropeptide Y levels in medication naive adolescents with major depressive disorder

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Neuropeptide Y (NPY) has been implicated in pathophysiology of anxiety and depression. It was proposed that NPY counteracts corticotropin-releasing factor-mediated stress effects to maintain emotional regulation.
Medine Yazici Gulec, Ozlem Albayrak Ozalmete, Mucahit Ozturk, Huseyin Gulec, Kemal Sayar, Samet Kose   +5 more
doaj  

The MacBrain Resource Center (MBRC) rhesus macaque embryonic brain histology datasets

Journal of Anatomy, EarlyView.
We introduce the MacBrain Resource Center (MBRC) Collections of rhesus macaque embryonic brain tissue. Here, we illustrate histo‐ and immunohistology from our dynamically growing Collection 6, which currently contains >10,000 zoomable and downloadable images from n = 14 male and female embryos from early to late in gestation.
Valeria Mendoza‐Silva, Emma Burke, Lucy Greene, Mikhail Rodov, Janja Kopić, Phil Barello, Yury M. Morozov, Keiko Moriya‐Ito, Chiaki Ohtaka‐Maruyama, Zeljka Krsnik, Pasko Rakic, Alvaro Duque   +11 more
wiley   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque postnatal brain histology datasets: Enabling new discoveries through NHP tissue and digital data Repositories

Journal of Anatomy, EarlyView.
The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva, Lucy Greene, Emma Burke, Cristina Canales, Julia Chocarro, Jose L. Lanciego, Khuleshwari Kurrey, Phil Barello, Aya Nusir, Nadine Kabbani, Kathleen S. Rockland, Dibyadeep Datta, Jon I. Arellano, Amy F. T. Arnsten, Yury M. Morozov, Bashir Ahmed, Zoltán Molnár, Caroline J. Zeiss, Pasko Rakic, Alvaro Duque   +19 more
wiley   +1 more source

Agonists for neuropeptide Y receptor subtypes NPY-1 and NPY-2 have opposite actions on rat nodose neuron calcium currents

, 1993
1. The whole-cell variation of the patch-clamp technique was used to study the effect of neuropeptide Y (NPY) and preferential agonists for the NPY-1 and NPY-2 receptor subtypes on voltage-dependent calcium currents in acutely dissociated postnatal rat ...
R. A. Gross, R. L. MacDonald, J. W. Wiley   +2 more
core   +1 more source

Transcriptomic profiling of subpopulations of mouse embryonic subplate neurons

Journal of Anatomy, EarlyView.
To study gene expression in subpopulations of cortical subplate neurons (Lpar1‐EGFP‐positive and D1B‐positive SpN clusters), we applied gene expression profiling, including bulk microarray analysis, single‐cell RNA sequencing (scRNA‐seq), and Visium spatial transcriptomics, and identified both overlapping and unique gene expression signatures ...
Hitomi Achiwa, Yuichiro Hara, Hideya Kawaji, Minori Oshima, Noe Kaneko, Ayumu Morioka, Anna Hoerder‐Suabedissen, Zoltán Molnár, Chiaki Ohtaka‐Maruyama   +8 more
wiley   +1 more source

Characterization of neuropeptide Y (NPY) receptors in human hippocampus

, 1991
We identified a 50 kDa neuropeptide Y (NPY) receptor from human hippocampus by affinity labeling. NPY specific binding and labeling of the receptor were inhibited in parallel by increasing concentrations of unlabeled NPY (IC= 0.27nM and0.18nM ...
Li, Wei, Hexum, Terry D
core   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Sympathetic NPY controls glucose homeostasis, cold tolerance, and cardiovascular functions in mice

Cell Reports
Summary: Neuropeptide Y (NPY) is best known for its effects in the brain as an orexigenic and anxiolytic agent and in reducing energy expenditure. NPY is also co-expressed with norepinephrine (NE) in sympathetic neurons.
Raniki Kumari, Raluca Pascalau, Hui Wang, Sheetal Bajpayi, Maria Yurgel, Kwaku Quansah, Samer Hattar, Emmanouil Tampakakis, Rejji Kuruvilla   +8 more
doaj   +1 more source