Neuropeptide Y knockout mice reveal a central role of NPY in the coordination of bone mass to body weight. [PDF]
Changes in whole body energy levels are closely linked to alterations in body weight and bone mass. Here, we show that hypothalamic signals contribute to the regulation of bone mass in a manner consistent with the central perception of energy status ...
Paul A Baldock+21 more
doaj +1 more source
Porcine neuropeptide Y (pNPY) administered into the third ventricle of the brain is known to elicit a powerful feeding response in steroid-treated ovariectomized and intact male rats. The present study compared the effects of pNPY and 3 structurally related peptides, human NPY (hNPY), an analog of NPY (NPY-A, [norLeu4]NPY) and peptide YY (PYY) on ...
Department of Obstetrics and Gynecology, University of Florida College of Medicine, Gainesville, FL 32610, U.S.A. ( host institution )+5 more
openaire +4 more sources
Detection of endogenous NPY release determined by novel GRAB sensor in cultured cortical neurons
Neuropeptide Y (NPY) is an abundantly expressed peptide in the nervous system. Its widespread distribution along with its receptors, both centrally and peripherally, indicates its broad functions in numerous biological processes.
Emma Kragelund Christensen+8 more
doaj +1 more source
Hypothalamic gene expression during voluntary hypophagia in the Sprague-Dawley rat on withdrawal of the palatable liquid diet, Ensure [PDF]
Copyright © 2014 Elsevier Inc.
Archer, Zoe A+2 more
core +1 more source
Impact of birth weight and gender on early postnatal hypothalamic energy balance regulatory gene expression in the young lamb [PDF]
Peer ...
Adam, C. L.+5 more
core +1 more source
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica+6 more
wiley +1 more source
Background The complex regulatory mechanism involved in ovarian follicular development is not completely understood. Neuronal neuropeptide Y (NPY) is involved in the regulation of feeding behavior, energy homeostasis, and reproduction behavior, while its
Yoko Urata+4 more
doaj +1 more source
NPY Signaling Inhibits Extended Amygdala CRF Neurons to Suppress Binge Alcohol Drinking
Binge alcohol drinking is a tremendous public health problem because it leads to the development of numerous pathologies, including alcohol abuse and anxiety.
K. Pleil+10 more
semanticscholar +1 more source
Charge Characteristics of Agouti-Related Protein Implicate Potent Involvement of Heparan Sulfate Proteoglycans in Metabolic Function. [PDF]
The endogenous melanocortin peptide agouti-related protein (AgRP) plays a well-known role in foraging, but its contribution to metabolic regulation is less understood.
Chen, Jihuan+9 more
core +1 more source
Lack of Spinal Neuropeptide Y Is Involved in Mechanical Itch in Aged Mice
Neuropeptide Y (NPY) signaling plays an essential role in gating the pruritic afferent information in the spinal cord. Recent studies revealed that the aging process down-regulated the expression of NPY in the central nervous system.
Huan Cui+11 more
doaj +1 more source