Results 191 to 200 of about 157,133 (211)
Some of the next articles are maybe not open access.
The Nrf2-Keap1-ARE Signaling Pathway: The Regulation and Dual Function of Nrf2 in Cancer
Antioxidants & Redox Signaling, 2010The NF-E2-related factor-2 (Nrf2) is a transcription factor that is ubiquitously expressed at low levels in all human organs. As Nrf2 regulates a major cellular defense mechanism, tight regulation is crucial to maintain cellular homeostasis. Activation of this pathway is important in preventing human diseases, such as cancer, neurodegenerative disease,
openaire +2 more sources
Biochemical Society. Transactions, 2015
The nuclear factor erythroid 2-related factor 2 (NRF2) transcription factor is a key player in the cellular antioxidant response and it also controls various other functions in a cell-type specific manner. Due to these key functions, a tight control of NRF2 expression and activity is essential.
Kurinna, Svitlana, Werner, Sabine
openaire +1 more source
The nuclear factor erythroid 2-related factor 2 (NRF2) transcription factor is a key player in the cellular antioxidant response and it also controls various other functions in a cell-type specific manner. Due to these key functions, a tight control of NRF2 expression and activity is essential.
Kurinna, Svitlana, Werner, Sabine
openaire +1 more source
2022
Breast cancer is still one of the leading cause of morality in women. Despite of all measures for early detection and prevention, there is no significant progress in the survival rates. One of the reasons for this is therapy resistance. Aquaporins, firstly described as cellular plumbing system, provided mechanisms for cancer cell motility and ...
openaire
Breast cancer is still one of the leading cause of morality in women. Despite of all measures for early detection and prevention, there is no significant progress in the survival rates. One of the reasons for this is therapy resistance. Aquaporins, firstly described as cellular plumbing system, provided mechanisms for cancer cell motility and ...
openaire
Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
Cancer Cell, 2021Hua Su +2 more
exaly
Thirty years of NRF2: advances and therapeutic challenges
Nature reviews. Drug discoveryDonna D. Zhang
semanticscholar +1 more source
NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer
Cell Metabolism, 2023Maolin Ge
exaly