Results 251 to 260 of about 200,244 (343)

Astaxanthin Reverses Oxidative Stress-Induced Dysfunction in Human Periodontal Ligament Stem Cells by Activating the Nrf2/ARE Pathway. [PDF]

Stem Cells Int
Chi J, Yu X, Zhang H, Jiao M, Wang P, Wang K, Wang T, Deng J.   +7 more
europepmc   +1 more source

MAPK15 controls cellular responses to oxidative stress by regulating NRF2 activity and expression of its downstream target genes

Lorenzo Franci, Giulia Vallini, Franca Maria Bertolino, Vittoria Cicaloni, Giovanni Inzalaco, Mattia Cicogni, Laura Tinti, Laura Calabrese, Virginia Barone, Laura Salvini, Pietro Rubegni, Federico Galvagni, M Chiariello   +12 more
openalex   +1 more source

Characterization of the Antioxidant Peptides Prepared From the Seed Kernel of Xanthoceras sorbifolium Using Enzymatic Hydrolysis: Molecular Docking Analysis and In Vitro Binding Studies

Food Safety and Health, EarlyView.
XSPH‐I exhibits excellent cellular antioxidant activity and cell protective effects. Four novel antioxidant peptides were screened from XSPH‐I peptide, and the newly synthetic peptide exhibits excellent antioxidant properties in vitro. ABSTRACT In this study, the antioxidant peptides (XSPH) from Xanthoceras sorbifolium oleifera were extracted and ...
Yalin Li, Chao Liu, Rong Sun, Jinyue Sun, Ye Shi, Shihai Lu, Dahu Zhang, Jinwei Qi, Xu Guo, Zhenlin Han, Ningyang Li   +10 more
wiley   +1 more source

Oroxylin A From <i>Scutellaria baicalensis</i> Improved Pulmonary Fibrosis of Radiation Pneumonia Through Ferroptosis by Nrf2. [PDF]

Can Respir J
Zhang W, Hao W, Gao X, Li K.
europepmc   +1 more source

Depressed TFAM promotes acetaminophen-induced hepatotoxicity regulated by DDX3X–PGC1α–NRF2 signaling pathway [PDF]

Sisi Chen, Yaling Cao, Zihao Fan, Ling Xu, Zhenzhen Pan, Yao Gao, Linlin Wei, Qiaoxin Wei, Yuan Tian, Xiangying Zhang, Mei Liu, Feng Ren   +11 more
openalex   +1 more source

Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review

Food Safety and Health, EarlyView.
Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra, Monika Bhadauria, Satendra Kumar Nirala   +2 more
wiley   +1 more source

Interplay of oxidative stress and Inflammasome activation and clinical indices in Parkinson's disease: insights from serum SIRT1, Nrf2, and NLRP3 levels and PDQ-39-a cross-sectional study. [PDF]

Front Neurosci
Aldossary KM, Hamza E, Kamel MM, Alsegiani AS, Alrubia S, Sarawi WS, El-Khateeb E, Eltantawy N, Mourad SA, Elshorbagi N, Khrieba MO.   +10 more
europepmc   +1 more source

Effects of the Pharmacological Modulation of NRF2 in Cancer Progression. [PDF]

Medicina (Kaunas)
Gelerstein-Claro S, Méndez-Valdés G, Rodrigo R.   +2 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

<i>KEAP1</i> mutations activate the NRF2 pathway to drive cell growth and migration, and attenuate drug response in thyroid cancer. [PDF]

Front Oncol
Bambach NE, Ricarte-Filho JC, Reichenberger ER, Hernandez-Padilla C, Hinkle K, Isaza A, Bauer AJ, Franco AT.   +7 more
europepmc   +1 more source