Results 251 to 260 of about 112,785 (303)

Inflammation, Immunity, and Cardiovascular Diseases

Med Research, EarlyView.
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo, Yan Liao, Rui Zhao, Zhaoyu Li, Kaikai Wang, Haoling Zhang, Pingxin Sun, Yadong Guo, Wangzheqi Zhang   +8 more
wiley   +1 more source

<i>Viola tianshanica</i> Maxim Extract Ameliorates Lipopolysaccharide Induced Acute Lung Injury by Regulating NLRP3 Inflammasome and Nrf2 Signaling Pathway. [PDF]

J Microbiol Biotechnol
Liu Y, Shi Y, Xu L, Wang X.
europepmc   +1 more source

Nrf2 Signaling: An Adaptive Response Pathway for Neurodegenerative Disorders

, 2016
Gerfo, Annalisa Lo, Petrozzi, Lucia, Chico, Lucia, Siciliano, Gabriele   +3 more
openaire   +3 more sources

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

Medicinal Research Reviews, EarlyView.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca, Mariana Feijó, Cátia V. Vaz, Bruno J. Pereira, Sandra Laurentino, Ana Palmeira‐de‐Oliveira, Sílvia Socorro   +6 more
wiley   +1 more source

Chinese traditional medicine complex hemorrhoidal analgesic cream promotes wound healing in diabetic rats after anal fistula surgery via Keap1/Nrf2 signaling pathway. [PDF]

Biochem Biophys Rep
Liu J, Yin Z, Tian X, Liu D, Wang C, Yuan H.   +5 more
europepmc   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Study on the Regulatory Effect of Water Extract of <i>Artemisia annua</i> L. on Antioxidant Function of Mutton Sheep via the Keap1/Nrf2 Signaling Pathway. [PDF]

Antioxidants (Basel)
Gang G, Gao R, Li R, Jin X, Xing Y, Yan S, Xu Y, Shi B.   +7 more
europepmc   +1 more source

Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling [PDF]

, 2018
Miner, Cathrine A., Miner, Jonathan J., Qian, Wei   +2 more
core   +1 more source

Depressed TFAM promotes acetaminophen-induced hepatotoxicity regulated by DDX3X-PGC1α-NRF2 signaling pathway. [PDF]

Mol Med
Chen S, Cao Y, Fan Z, Xu L, Pan Z, Gao Y, Wei L, Wei Q, Tian Y, Zhang X, Liu M, Ren F.   +11 more
europepmc   +1 more source