Diversity of Nonribosomal Peptide Synthetase Genes in the Microbial Metagenomes of Marine Sponges
Genomic mining revealed one major nonribosomal peptide synthetase (NRPS) phylogenetic cluster in 12 marine sponge species, one ascidian, an actinobacterial isolate and seawater.
Ute Hentschel +3 more
doaj +1 more source
PCR-based Screening Approach: A Rapid Method to Detect the Biosynthetic Potential of Antimicrobials in Actinobacterial Strains [PDF]
NAILA NOUREEN +4 more
doaj +1 more source
Additional file 11: Figure S3 of Genus level analysis of PKS-NRPS and NRPS-PKS hybrids reveals their origin in Aspergilli [PDF]
Branch C from hybrid maximum likelihood phylogeny (Fig. 1). Sections and species groups indicated by tip color; Orientation of hybrids N-type (NRPS-PKS) and P-type (PKS-NRPS) indicated by tip shape.
Tammi Vesth (399962) +2 more
core +1 more source
Additional file 12: Figure S4 of Genus level analysis of PKS-NRPS and NRPS-PKS hybrids reveals their origin in Aspergilli [PDF]
Branch D from hybrid maximum likelihood phylogeny (Fig. 1). Sections and species groups indicated by tip color; Orientation of hybrids N-type (NRPS-PKS) and P-type (PKS-NRPS) indicated by tip shape.
Tammi Vesth (399962) +2 more
core +1 more source
Genetic engineering (GE) overcomes BCA limits, enabling robust, scalable crop protection. “Super Bioagents” (SBs) use optimized SSs to enhance bioactive molecule delivery. Optimizing SSs enhance precise, sustainable effector deployment for stable disease suppression. SBs use microbiome‐informed design for scalable, next‐gen sustainable crop protection.
Michael Dare Asemoloye
wiley +1 more source
Additional file 10: Figure S2 of Genus level analysis of PKS-NRPS and NRPS-PKS hybrids reveals their origin in Aspergilli [PDF]
Branch B from hybrid maximum likelihood phylogeny (Fig. 1). Sections and species groups indicated by tip color; Orientation of hybrids N-type (NRPS-PKS) and P-type (PKS-NRPS) indicated by tip shape.
Tammi Vesth (399962) +2 more
core +1 more source
Connecting Thoughts and Actions: A Managerial Process Model on Circular Business Model Innovation
ABSTRACT Addressing environmental grand challenges such as resource scarcity requires circular business model innovation (CBMI) that enables firms to efficiently close and slow resource cycles through novel activity systems. Drawing on a grounded theory approach based on 59 in‐depth interviews with top managers from Swiss SMEs, we developed a process ...
Fabian Takacs, Karolin Frankenberger
wiley +1 more source
Chemoenzymatic reactions using the siderophore synthetase DesD from Salinispora tropica and hydroxamic acid substrates (native, non‐native) with different multiplicities (monomer, dimer) and components (homo‐/heterodimer) followed different reaction trajectories, which biased the architectures of the chelator major products and indicated DesD contains ...
Callum A. Rosser +2 more
wiley +1 more source
Neck Reflex Points: A New Clinical Test? Prevalence in Two Cohorts and Its Covariates
Background: Neck reflex points (NRPs) are 2 × 6 potentially tender areas of the neck, denominated NRP-C0 to NRP-C7. They are different from muscular trigger points and become tender in response to chronic trigeminal irritation. NRP examination has a high
Stefan Weinschenk +4 more
doaj +1 more source
Rheumatoid arthritis (RA) is the most prevalent inflammatory arthropathy globally and remains incurable nowadays. Herein, an M2 macrophage‐mimetic hybrid nanoplatform (Cel@M2‐L‐MSN) is constructed for concerted RA therapy through joint‐specific accumulation, on‐demand drug release, inflammation resolution, ROS clearance, along with macrophage ...
Yi Xiao +11 more
wiley +1 more source

