Results 81 to 90 of about 14,800 (259)

Hormonal regulation and differential expression of neuropilin (NRP)-1 and NRP-2 genes in bovine granulosa cells [PDF]

open access: yesReproduction, 2006
Abstract Although much is known about the biology of vascular endothelial growth factor (VEGF) and its receptors, little is known about the role of the VEGF receptors neuropilin (NRP)-1 and NRP-2 in the process of bovine follicle development.
Takashi, Shimizu   +5 more
openaire   +2 more sources

Biosynthesis of Amino Acid Derived α‑Pyrones by an NRPS–NRPKS Hybrid Megasynthetase in Fungi [PDF]

open access: yes, 2020
A nonribosomal peptide synthetase (NRPS)-nonreducing polyketide synthase (NRPKS) hybrid enzyme (AnATPKS) from Aspergillus niger was shown to produce amino acid derived α-pyrone natural products (pyrophen and campyrone B).
Yang Hai (830201)   +2 more
core   +4 more sources

In Vivo Quantification of Surfactin Nonribosomal Peptide Synthetase Complexes in Bacillus subtilis

open access: yesMicroorganisms
Surfactin, a potent biosurfactant produced by Bacillus subtilis, is synthesized using a non-ribosomal peptide synthetase (NRPS) encoded by the srfAA-AD operon.
Maliheh Vahidinasab   +6 more
doaj   +1 more source

Architecture of a PKS-NRPS hybrid megaenzyme involved in the biosynthesis of the genotoxin colibactin [PDF]

open access: yes, 2023
International audienceThe genotoxin colibactin produced by Escherichia coli is involved in the development of colorectal cancers. This secondary metabolite is synthesized by a multi-protein machinery, mainly composed of non-ribosomal peptide synthetase ...
Pauline Macheboeuf   +7 more
core   +1 more source

The Lactococcus lactis KF147 nonribosomal peptide synthetase/polyketide synthase system confers resistance to oxidative stress during growth on plant leaf tissue lysate

open access: yesMicrobiologyOpen, 2018
Strains of Lactococcus lactis isolated from plant tissues possess adaptations that support their survival and growth in plant‐associated microbial habitats.
Benjamin L. Golomb   +3 more
doaj   +1 more source

Mining the Yucatan Coastal Microbiome for the Identification of Non-Ribosomal Peptides Synthetase (NRPS) Genes

open access: yesToxins, 2020
Prokaryotes represent a source of both biotechnological and pharmaceutical molecules of importance, such as nonribosomal peptides (NRPs). NRPs are secondary metabolites which their synthesis is independent of ribosomes.
Mario Alberto Martínez-Núñez   +1 more
doaj   +1 more source

Genomics of NRPS/PKS Biosynthetic Gene Clusters in Cyanobacteria [PDF]

open access: yes, 2017
Cyanobacteria are well-known producers of a broad range of natural products of diverse chemical structures. Many of these compounds are the products of non-ribosomal peptide synthetase (NRPS) or polyketide synthase (PKS) pathways.
Alexandra Calteau   +5 more
core   +1 more source

Additional file 13: Figure S5 of Genus level analysis of PKS-NRPS and NRPS-PKS hybrids reveals their origin in Aspergilli [PDF]

open access: yes, 2019
Branch E from hybrid maximum likelihood phylogeny (Fig. 1). Sections and species groups indicated by tip color; Orientation of hybrids N-type (NRPS-PKS) and P-type (PKS-NRPS) indicated by tip shape.
Tammi Vesth (399962)   +2 more
core   +1 more source

Combination Methods for Screening Marine Actinomycetes Producing Potential Compounds as Anticancer

open access: yesIndonesian Journal of Biotechnology, 2007
Marine actinomycetes is a robust source of secondary metabolites including anticancer compounds . The objective of this research was to select marine actinomycetes producing potential compounds as anticancer used combination methods that consist of ...
Yuyun Farida, Jaka Widada, Edy Meiyanto
doaj   +1 more source

Predicted PKS and hybrid PKS-NRPS biosynthetic clusters. [PDF]

open access: yes, 2016
Predicted PKS and hybrid PKS-NRPS biosynthetic clusters.
Roslyn D. Noar (3158139)   +1 more
core   +1 more source

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