Results 121 to 130 of about 14,800 (259)
ABSTRACT Child protection and welfare systems are entrusted with significant power by governments and are therefore a significant focus of monitoring activities. Monitoring can help to build a better child protection system and to ensure child safety; track policy and legislative implementation and resource allocation; contribute to preventing systemic
Kenneth Burns +3 more
wiley +1 more source
The decades-long gap in antibiotic discovery has led to a significant health crisis due to antimicrobial resistance (AMR). The bacterial genus Xenorhabdus, which forms symbiotic relationships with the soil nematode Steinernema, are known to secrete a ...
Ritisha Dey +9 more
doaj +1 more source
Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution
Modifying the non-ribosomal peptide synthase (NRPS)/polyketide synthase (PKS) pathway to generate novel non-ribosomal peptides often results in a loss of productivity.
Takayoshi Awakawa +10 more
doaj +1 more source
Limbal cystotomy by fine needle aspiration of a translucent iris cyst in a horse
Summary A 4‐year‐old Cremello crossbred mare was referred to the Equine Veterinary Teaching Hospital of Utrecht University for a translucent iris cyst from the dorsal pupillary margin corpora nigra in the right eye. Although noninvasive diode laser treatment is the preferred method of pigmented cyst ablation, two attempts did not result in disruption ...
A. L. Hendrikx +5 more
wiley +1 more source
Caffeic acid is a central metabolite in the fungal bioluminescence pathway. We identified and characterized caffeylpyruvate hydrolase from Neonothopanus gardneri (ngarCPH) and demonstrate its ability to hydrolyze fungal oxyluciferin into caffeic and pyruvic acids, confirming a complete and self‐sustained fungal bioluminescence cycle.
Caio K. Zamuner +8 more
wiley +1 more source
The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1
ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu +2 more
wiley +1 more source
ABSTRACT Across the Western world, joint legal and physical custody is increasingly becoming the default post‐separation arrangement. While family policy and law encourage such arrangements, they may not suit every situation. In child‐custody court disputes, courts must consider whether sole legal custody is the best alternative for the child in each ...
Johanna Finnström, Ann‐Zofie Duvander
wiley +1 more source
Combination Methods for Screening Marine Actinomycetes Producing Potential Compounds as Anticancer
Marine actinomycetes is a robust source of secondary metabolites including anticancer compounds . The objective of this research was to select marine actinomycetes producing potential compounds as anticancer used combination methods that consist of ...
Yuyun Farida, Jaka Widada, Edy Meiyanto
doaj
Outcomes after resection of pancreatic ductal adenocarcinoma remain highly variable, and existing prognostic models lack sufficient accuracy. Here, the authors aimed to improve survival prediction by integrating transcriptome‐based subtyping into a validated clinical model and applying it to a multicenter real‐world cohort of fresh‐frozen resection ...
Marjolein F. Lansbergen +20 more
wiley +1 more source
To NRP or Not to NRP, That Is the Question…
John O O, Ayorinde +2 more
openaire +3 more sources

