Results 171 to 180 of about 260,886 (316)

LAURA Completes the Osimertinib Treatment Jigsaw Puzzle of EGFR+ NSCLC from Stage IB to IV: Adjuvant Osimertinib Significantly Improves PFS and CNS Progression in Unresectable Stage III EGFR-Mutated NSCLC Compared to Placebo (LAURA, NCT03521154)

open access: yes
Faustine X Luo,1,2 Zhaohui Arter,1,2 Sai-Hong Ignatius Ou,1,2 Misako Nagasaka1– 3 1Chao Family Comprehensive Cancer Center, Orange, CA, 92868, USA; 2University of California Irvine School of Medicine, Orange, CA, 92868, USA; 3St.
Nagasaka M, Arter Z, Luo FX, Ou SI
core  

Clinical Implementation and Oncological Relevance of Molecular Profiling in Brain Metastases Patients—A Multicenter Retrospective Cohort Study

open access: yesInternational Journal of Cancer, EarlyView.
While current guidelines recommend the analysis of established cancer driver genes in brain metastases, little is known about its real‐life implementation. This multicenter study revealed an upward trend in the profiling rates of surgically treated brain metastases over the past decade, with up to 60% of brain metastases samples undergoing analysis ...
Maria Nikolaeva   +25 more
wiley   +1 more source

PET/CT and PET/MRI in Cancer Diagnosis and Management: A Comparative Clinical Perspective

open access: yesiMetaMed, EarlyView.
This review compares PET/CT and PET/MRI in cancer imaging, highlighting their complementary roles for precise diagnosis and staging. It evaluates their technical strengths, clinical performance across various cancers, and future directions, including AI and novel tracers.
Zijian Ding   +5 more
wiley   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

open access: yesiNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

PLNR≤20% may be a benefit from PORT for patients with IIIA-N2 NSCLC: a large population-based study

open access: yes, 2018
Xiaoling Shang, Zhenxiang Li, Jiamao Lin, Haiyong Wang, Zhehai Wang Department of Internal Medicine-Oncology, Shandong Cancer Hospital and Institute, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan ...
Li Z, Shang X, Lin J, Wang H, Wang Z
core  

The Endothelial CXCR Family in Vascular Health and Disease

open access: yesiNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu   +4 more
wiley   +1 more source

c‐Met‐Targeted Imaging Agents: Progress and Challenges

open access: yesiRADIOLOGY, EarlyView.
This review summarizes recent advances in c‐Met‐targeted imaging probes, including hepatocyte growth factor (HGF) ligands, antibodies, peptides, and small molecules across magnetic resonance imaging (MRI), positron emission tomography (PET), single‐photon emission computed tomography (SPECT), and optical imaging modalities.
Yonghao Li   +4 more
wiley   +1 more source

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