Results 181 to 190 of about 278,336 (309)

Identification of JAML as an Immune-Associated Prognostic Marker in Non-Small Cell Lung Cancer. [PDF]

Lung Cancer (Auckl)
Tian Q, Zhang F, Han C.
europepmc   +1 more source

Advances in Immunological Combination Therapy for Colorectal Cancer

iMetaMed, EarlyView.
Review the progress of combined immunotherapy for colorectal cancer. ABSTRACT Immune checkpoint inhibitors (ICIs) have been utilized extensively and shown to be therapeutically beneficial in the treatment of solid tumors in recent years. Nonetheless, considerable heterogeneity in Colorectal cancer (CRC) requires careful consideration.
Jiayue Wu, Rongbo Wen, Tianshuai Zhang, Fuao Cao, Xiaoming Zhu, Liqiang Hao, Wei Zhang, Guanyu Yu   +7 more
wiley   +1 more source

CNTN5 Promotes Invasion and Metastasis in Non-Small Cell Lung Cancer by Regulating YAP1 Nuclear Translocation. [PDF]

J Gene Med
Wang J, Wang M, Yin Y, Zeng A, Chen K, Xu Z, Dai J.   +6 more
europepmc   +1 more source

A Pan‐Cancer Single‐Cell Atlas of Bone Metastases Reveals Convergent Malignant Programs and Coordinated Immune Dysfunction

iMetaMed, EarlyView.
A pan‐cancer atlas deciphers tumor‐induced reprogramming in bone metastases. Malignant evolution toward MYC/proliferation is a hallmark of bone metastases. Niche‐mediated immune dysfunction is characterized by immature pDCs, impaired antigen presentation and phagocytosis in TAMs, and exhausted T cells.
Yitong Pan, Zhou Yang, Junyuan Deng, Feng Liu, Guang Lei   +4 more
wiley   +1 more source

High‐Concordance Detection Across Diverse Biospecimens EGFR Mutation in a Large‐Scale NSCLC Cohort Using Droplet Digital PCR and Next‐Generation Sequencing

iMetaMed, EarlyView.
DdPCR provides reliable detection and quantification of clinically relevant EGFR mutations across multiple specimen types and processing states. ABSTRACT Accurate detection and quantification of EGFR mutations are essential for molecular stratification in non‐small cell lung cancer (NSCLC).
Ming Liu, Linping Lu, Qifang Lei, Lingxiang Zhu, Xiaoni Zhang, Yuanyuan Liu, Xiaojing Ren, Shimin Liu, Shaochen Cheng, Mingyan Xu, Chao Lu, Yan Peng, Kamen Ivanov, Jia Gu, Wenmei Su, Hengrui Liu, Yong Guo, Shifu Chen   +17 more
wiley   +1 more source

Integrated single-cell and bulk transcriptomic analysis reveals an epithelial cell-derived prognostic and immunotherapeutic signature with ADAM12 as a key functional regulator in non-small cell lung cancer. [PDF]

Transl Oncol
Liu H, Yu J, Jiang Y, Ma X, Luo W, Guo S, Tong L, Lu Y, Zhang Z, Li C, Qi J, Qin T.   +11 more
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

NLRC4 and NLRP3 in tissues as potential biomarkers for the diagnosis of non-small cell lung cancer in pulmonary tuberculosis. [PDF]

Front Cell Infect Microbiol
Zhang Z, Zhao Z, Xie S, Guo B, Cai C, Wu C, Hao X, Ni J, Cui H, Xiong M.   +9 more
europepmc   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Advancements in Immunotherapy for Lung Cancer: A Meta-Analysis of Clinical Trial Outcomes. [PDF]

Clin Respir J
Jiao Y, Zhao Y.
europepmc   +1 more source