Results 191 to 200 of about 260,886 (316)

The Prognostic Value of EDRIC and Its Association With Radiation‐Induced Lymphopenia in Patients With Esophageal Cancer Undergoing Radical Radiotherapy: A Single‐Center Chinese Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to evaluate the predictive value of the estimated dose of radiation to immune cells (EDRIC) in patients with esophageal cancer receiving radical radiotherapy. We retrospectively reviewed the data of patients with esophageal cancer who underwent definitive radiotherapy at our institution.
Yue Ke, Chen Yang, Yu‐Xing Li, Xiao‐Xiao Liu, Xiao Liu, Jia‐Min Gao, Hong‐Bing Ma   +6 more
wiley   +1 more source

Downregulation of PRPS2 inhibits tumor growth of non-small cell lung cancer by suppressing PI3K/AKT signaling. [PDF]

Front Med (Lausanne)
Xu Q, Liu Q, Ke C, Hou P.
europepmc   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Understanding immune checkpoint inhibitor efficacy through spatial decoding of the lung cancer tumor immune microenvironment. [PDF]

J Clin Invest
Zou T, Minna JD.
europepmc   +1 more source

LKB1 Loss Sensitizes Lung Tumor Spheres to Mitomet‐Induced Ferroptosis, and These Effects are Enhanced by mTOR Inhibition

Molecular Carcinogenesis, EarlyView.
ABSTRACT Owing to their robust antioxidant defense mechanisms, cancer stem‐like cells (CSCs) maintain a low level of oxidative stress, which is crucial for preserving stemness and pluripotency. Therefore, agents that either directly generate reactive oxygen species (ROS) or inhibit the antioxidant defense systems can selectively induce oxidative cell ...
Xueqing Liang, Ali Nakhi, Peter I. Dosa, Gunda I. Georg, Fekadu Kassie   +4 more
wiley   +1 more source

Epidemiology and Real-World Outcomes in Patients with Human Epidermal Growth Factor Receptor 2 (HER2)-Mutant Non-small Cell Lung Cancer by Region: A Targeted Literature Review. [PDF]

Target Oncol
Goto K, Hayashi H, Maruti SS, Zettl H, Mittal L, Pathak S, Le X.   +6 more
europepmc   +1 more source

Genetic Alterations in the SERPIN Gene Family as Predictors of Immune Checkpoint Therapy Efficacy in Melanoma and Non‐Small Cell Lung Cancer

Medicine Advances, EarlyView.
This study demonstrated a clear association between serine protease inhibitor (SERPIN) gene alterations and clinical outcomes in patients with melanoma and non‐small cell lung cancer receiving immune checkpoint inhibitor therapy across five cohorts.
Jieqiong Li, Di Wang, Yuxin Wang, Lixia Wang, Jinmei Luo, Yi Xiao   +5 more
wiley   +1 more source

Practice-Changing Advances in Systemic Therapies Shaping the Landscape of Lung Cancer in 2025. [PDF]

Cancer Innov
Zhou Z, Gao W, Li MSC, Zhou Q.
europepmc   +1 more source

Gene Expression Profiling of EGFR, FGFR2, PIK3CA, PTEN, SMAD4, STK11, and TP53 in Cell-Free RNA From Exhaled Breath Condensate: Diagnostic, Prognostic, and Therapeutic Implications in Advanced Lung Adenocarcinoma. [PDF]

Cancer Rep (Hoboken)
Latifova S, Genis U, Karakus HS, Korba K, Ozgur S, Aldag C, Goksel T, Pelit L, Gunduz C, Vardarli AT.   +9 more
europepmc   +1 more source

Normoxic HIFα-mediated metabolic rewiring in cancer as a novel therapeutic target of tumor heterogeneity. [PDF]

Cancer Metab
Sánchez-Castillo A, Lommen JGE, Consten D, Savelkouls K, Barbeau LMO, Rouschop KMA, Vooijs MA, Kampen KR.   +7 more
europepmc   +1 more source