Results 271 to 280 of about 29,671 (305)

An Implantable Optogenetics‐Engineered Hydrogel for Amelioration of Rheumatoid Arthritis through Light‐Controlled Metabolic Reprogramming of Synovial Macrophages

Advanced Science, EarlyView.
An implantable hydrogel is designed to enable in situ and on‐demand secretion of GLP‐1 in synovium through blue light irradiation to activate GLP‐1R/HK2/VDAC1 pathway for upregulating tricarboxylic acid cycle and oxidative phosphorylation in macrophage, facilitating tissue repair and bone erosion recovery.
Dahai Hu, Yaru Sun, Qi Lu, Yi Zhang, Jieruo Li, Huige Hou, Huajun Wang, Hui Tang, Yunsong Zhang, Xiaofei Zheng, Qingsong Mei   +10 more
wiley   +1 more source

Unwrapping the Dodecaborane Core: Structure, Electronic Properties, and Chemical Reactivity Across the Complete [B₁₂I_<i>n</i>]^- Series (<i>n</i> = 11-1). [PDF]

J Am Chem Soc
Shao Q, Cao W, Knorke H, Behrend KA, Kaur J, Rohdenburg M, Volke D, Kenttämaa HI, Hu Z, Sun Z, Warneke J, Sun H, Wang XB.   +12 more
europepmc   +1 more source

Synergistic Spin‐Polarization and Single‐Atom Engineering in Magnetic Heterojunctions for Efficient Solar Water Splitting

Advanced Science, EarlyView.
High‐throughput screening led to the identification of 67 Z‐scheme heterojunctions (comprising 2D magnetic transition metal halides and non‐magnetic transition metal chalcogenides). For CrI3/MoTe2 and CrI3/WTe2, electronic structure analysis demonstrated that synergistic crystallographic point group and built‐in electric field effects generate a ...
Hongyang Ren, Zhenzhou Guo, Huirong Wu, Peilin Huang, Jie Yang, Jie Zhang, Guangqian Ding, Hongkuan Yuan, Biao Wang   +8 more
wiley   +1 more source

Strategic synthesis of FLPClusters toward catalysis. [PDF]

Nat Commun
Geng Z, He A, You X, Wu Q, Wang J, Guo H, Li S, Xie Z, Gong X, Yang M, Zuo D, Huo R, Li F, Zheng N, Shen H.   +14 more
europepmc   +1 more source

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

Advanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie, Ruixi Yang, Xiaotong Wang, Ping Jia, Xueqi Zhang, Yaqi Dai, Xue Bai, Sijia Duan, Yufeng Li, Peng Zheng, Xin Tian, Li Jiang, Chao Wang   +12 more
wiley   +1 more source

TROP2-targeted NIR-II fluorescence imaging for visualizing surgical margins and metastatic sentinel lymph nodes in breast cancers. [PDF]

Proc Natl Acad Sci U S A
Lou KL, Bai JW, Liu HT, Lin LL, Li CX, Gao YY, Lin SJ, Pei YF, Wei XL, Chen YX, Tang YY, Chen HY, Li ZY, Guo R, Tang SC, Wu CL, Zhang GJ.   +16 more
europepmc   +1 more source

Tuning nuclear rheology through transient chromatin cross-links. [PDF]

Phys Rev E
Zhang YD, Wu CH, Shi HX, Merlitz H, Bloom KS, Forest MG, Wu CX, Cao XZ.   +7 more
europepmc   +1 more source

Conjugation Lock-In Reinforced Sulfur-Heteropolycyclic Covalent Organic Frameworks with Asymmetric Electron Distribution for Photocatalytic Aerobic Oxidation Reactions. [PDF]

J Am Chem Soc
Yang J, Gao S, Zhao Z, Xu X, Liu S, Xu M, Xue W, Dong F, Li S, Thomas A, Cheng C.   +10 more
europepmc   +1 more source

Accuracy of Magnetic Resonance Spectroscopy-Detected Fumarate Peak for Diagnosing Fumarate Hydratase Deficiency in Uterine Leiomyomas: A Prospective Study. [PDF]

Korean J Radiol
Liu G, Yu W, Pan S, Luo Y, Chen J, Zhu M, Wang Z, Song Y, Zhang J, Xu J, Zhou Y, Ma J, Wu G.   +12 more
europepmc   +1 more source

The funding effectiveness in chemistry at the National Natural Science Foundation of China: research progress on the fundamentals and applications of zeolite materials. [PDF]

Natl Sci Rev
Dai WL, Chen LH, Yao C, Su BL, Yang JL, Gao FX.   +5 more
europepmc   +1 more source