Results 61 to 70 of about 750,062 (296)
Axon regeneration impediment: the role of paired immunoglobulin-like receptor B
Regenerative capacity is weak after central nervous system injury because of the absence of an enhancing microenvironment and presence of an inhibitory microenvironment for neuronal and axonal repair.
Jing Liu, Yan Wang, Wei Fu
doaj +1 more source
The Rho/Rho-associated coiled-coil containing protein kinase (Rho/ROCK) pathway is a major signaling pathway in the central nervous system, transducing inhibitory signals to block regeneration.
Jing Liu, Hong-yan Gao, Xiao-feng Wang
doaj +1 more source
Olfactory bulb tissue transplantation inhibits P2X2/3 receptor-mediated neuropathic pain. However, the olfactory bulb has a complex cellular composition, and the mechanism underlying the action of purified transplanted olfactory ensheathing cells (OECs ...
Hao Zhao+9 more
doaj +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Measuring subhalo mass in redMaPPer clusters with CFHT Stripe 82 Survey [PDF]
Based on observations obtained with MegaPrime/MegaCam, a joint project of CFHT and CEA/DAPNIA, at the Canada-France-Hawaii Telescope (CFHT), which is operated by the National Research Council (NRC) of Canada, the Institut National des Science de l ...
Ran Li+12 more
semanticscholar +1 more source
Amentoflavone is a natural biflavone compound with many biological properties, including anti-inflammatory, antioxidative, and neuroprotective effects. We presumed that amentoflavone exerts a neuroprotective effect in epilepsy models.
Zhen Zhang+5 more
doaj +1 more source
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li+10 more
wiley +1 more source
Quantum teleportation of photonic qudits using linear optics
Shanghai Research Challenge Fund; New York University Global Seed Grants for Collaborative Research; National Natural Science Foundation of China [61571301, D1210036A, 11674100]; NSFC Research Fund for International Young Scientists [11650110425 ...
Chenyu Zhang+5 more
semanticscholar +1 more source
Summary: Background: Childhood obesity is a critical public health concern in China. This study identified the key determinants of childhood obesity in China and provided recommendations for future intervention strategies.
Yanfen Jiang+12 more
doaj +1 more source
Loss of Stat3 in Prx1+ Progenitors Impairs Molar Root Development
Stat3 critically regulates mandibular first molar and alveolar bone morphogenesis. Conditional ablation of Stat3 disrupts the osteogenic capacity of Prx1+ mesenchymal progenitors, as evidenced across in vivo and in vitro models. Abstract Signal Transducer and Activator of Transcription 3 (Stat3) acts as a central transcriptional modulator coordinating ...
Xin Feng+10 more
wiley +1 more source