Results 111 to 120 of about 75,562 (190)

What anabolic–androgenic steroids reveal about the limits of current harm reduction models

Addiction, EarlyView.
Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski, Jason M. Nagata, Suzanne Nielsen   +2 more
wiley   +1 more source

Seminal Plasma Exosomal miRNA Profiling Reveals hsa‐miR‐7‐5p as a Key Regulator of Sperm Motility in Asthenozoospermia

Andrology, EarlyView.
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu, Meng‐Li Cui, Wen‐Jing Yuan, Jia‐Ning Zhang, Shuo Zhang, Xi‐Qiao Yao, Ruo‐Qing Li, Jin‐Feng Li, En‐Zhong Li   +8 more
wiley   +1 more source

Aspirations‐Capabilities of School‐to‐Work Transition in a Migratory Context: A Case of Thai Tertiary‐Level Migrants in Taiwan

Asia Pacific Viewpoint, EarlyView.
ABSTRACT This article explores aspirations‐capabilities of Thai migrants who transitioned from tertiary education to employment in Taiwan. Drawing on semi‐structured interviews with 23 Thai migrants, this study unpacks three distinct mobility trajectories under a processual perspective.
Pakorn Phalapong
wiley   +1 more source

Effect of non-starch polysaccharides and bile acid supplementation on nutrient digestibility, bile acid balance, faecal waste production and characteristics of yellowtail kingfish (Seriola lalandi)

Aquaculture Reports
Effects of non-starch polysaccharides (NSP) and bile acid supplementation (sodium taurocholate, STC) on nutrient digestibility, bile acid balance, faecal waste production and characteristics were investigated in yellowtail kingfish (Seriola lalandi). The
Yaqing Zhang, Roel M. Maas, Pim Hilgers, Peter Horstmann Zuther, Fotini Kokou, Thomas W.O. Staessen, Johan W. Schrama   +6 more
doaj   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

NePO: Neural Point Octrees for Large‐Scale Novel View Synthesis

Computer Graphics Forum, EarlyView.
We introduce Neural Point Octrees (NePOs), a scalable radiance field representation that organises point clouds hierarchically for efficient optimisation and rendering of large scale scenes. NePOs enable level of detail selection, joint refinement of appearance and camera poses, and real‐time rendering of hundreds of millions of points.
Noah Lewis, Darius Rückert, Marc Stamminger, Linus Franke   +3 more
wiley   +1 more source

How to spend $3.92 billion: stabilizing neighborhoods by addressing foreclosed and abandoned properties [PDF]

The Housing and Economic Recovery Act of 2008 created the Neighborhood Stabilization Program (NSP), under which states, cities, and counties will receive a total of $3.92 billion to acquire, rehabilitate, demolish, and redevelop foreclosed and abandoned ...
Mallach, Alan
core  

Impact of Electronic Cigarette Use on the Oral Microbiota: A Systematic Review

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To examine whether the oral microbiota of e‐cigarette users differs from that of never smokers and current smokers. Materials and Methods PubMed, Scopus and Web of Science were searched on 27 August 2025. Human studies using molecular methods to compare oral microbiota in saliva, subgingival plaque and oral mucosal swabs among e‐cigarette ...
Giusy Rita Maria La Rosa, Lakshman Perera Samaranayake, Egija Zaura, Ang Sun, Virginia Fuochi, Pio Maria Furneri, Jan Kowalski, Karol Myszel, Iain Chapple, Riccardo Polosa   +9 more
wiley   +1 more source

Optimization of subcritical water extraction, UPLC–triple–TOF–MS/MS analysis, antioxidant and α-glucosidase inhibitory activities of anthocyanins from Nitraria sibirica Pall. fruits

Food Chemistry: X
This study aimed to optimize subcritical water extraction process, characterize chemical composition and investigate the biological activities of Nitraria sibirica Pall. (NSP) anthocyanin. Overall, the optimization was achieved under following conditions:
Lichengcheng Ren, Qi Dong, Zhenhua Liu, Yue Wang, Nixia Tan, Honglun Wang, Na Hu   +6 more
doaj   +1 more source

Outcome and cost‐effectiveness of transdiagnostic cognitive behavioral therapy compared with management as usual for youth with common mental health problems: Long‐term results from the Mind‐My‐Mind randomized trial

Journal of Child Psychology and Psychiatry, EarlyView.
Background Credible long‐term outcomes from randomized trials evaluating the effectiveness and cost‐effectiveness of preventive programs for mental health problems are needed. We compared long‐term effects of the Mind My Mind (MMM) transdiagnostic cognitive behavioral therapy (CBT) program to management as usual (MAU). Methods The study was a pragmatic,
Ditte Vassard, Martin Køster Rimvall, Rasmus Trap Wolf, Robin Christensen, Sabrina M. Nielsen, Kerstin Jessica Plessen, Frank Verhulst, Niels Bilenberg, Per Hove Thomsen, Mikael Thastum, Simon‐Peter Neumer, Anne Katrine Pagsberg, Wendy K. Silverman, Christoph U. Correll, Pia Jeppesen   +14 more
wiley   +1 more source