Results 131 to 140 of about 75,562 (190)

Hydroxyl radical footprinting modification reveals an intradomain communication pathway in EFL1 disrupted by a Shwachman‐Diamond syndrome‐associated mutation

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Shwachman‐Diamond syndrome (SDS) is a rare genetic disorder characterized by pancreatic insufficiency and neutropenia. While most cases are linked to mutations in the SBDS gene, some involve mutations in the GTPase EFL1. This protein works with SBDS to release the anti‐association factor eIF6 from the 60S ribosomal subunit during ribosome ...
Jonathan A. Zúñiga‐Domínguez, Rohit Jain, Martín González‐Andrade, Erik R. Farquhar, Mark R. Chance, Abril Gijsbers, Nuria Sánchez‐Puig   +6 more
wiley   +1 more source

MaNAC46 Orchestrates Jasmonic Acid‐Induced Senescence by Coordinating Chlorophyll Catabolism, ROS Homeostasis and Autophagy in Banana

Plant Biotechnology Journal, EarlyView.
Subham Bhakta, Himanshu Tak, Sanjana Negi, Vitthal Barvkar, Namrata Waghamare, Anand Ballal, Sudhir Singh   +6 more
wiley   +1 more source

Antivirals Targeting Coronavirus RNA‐Dependent RNA Polymerase and Main Protease: From Mechanisms of Action to Outcomes in COVID‐19 Clinical Trials

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
The target sites of COVID‐19 antivirals discussed in the present opinion paper, namely the RNA dependent RNA polymerase Nsp12 and of the main viral protease Nsp5, are indicated by a red star in the overview of the replication cycle of coronavirus SARS‐CoV‐2.
Harald Brüssow
wiley   +1 more source

Molecular Mechanisms of Algicidal Bacteria in Controlling Harmful Algal Blooms: Advances in Bacteria‐Algae Interactions

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
This review elucidates the molecular mechanisms of algicidal bacteria, highlighting critical behaviours like chemotaxis, quorum sensing and extracellular vesicle release. It details how these actions disrupt algal cellular integrity, photosynthesis and calcium homeostasis, providing a theoretical foundation for controlling harmful algal blooms ...
Jiaxin Wang, Binfu Xu, Lixing Huang
wiley   +1 more source

Drug use among people in prison: A global review of epidemiology, harms and interventions

Addiction, Volume 121, Issue 4, Page 749-764, April 2026.
Abstract Background and aims People who use drugs are overrepresented in the criminal justice system. We aimed to provide a broad synthesis of the epidemiology, harms and interventions related to drug use and drug use disorders among incarcerated adults worldwide, and highlight gaps in evidence and practice.
Louis Favril, John Strang, Seena Fazel
wiley   +1 more source

All-cause mortality and overdose deaths among 4192 people who inject drugs in Stockholm: a 10-year register-based cohort study. [PDF]

Harm Reduct J
Holmén E, Hammarberg A, Kåberg M.
europepmc   +1 more source

Genetic Diversity Impacts Climate‐Induced Species Range Shifts

Ecology Letters, Volume 29, Issue 4, April 2026.
Genetic diversity may buffer species against climate‐driven range contractions and facilitate expansions, but its role at a global scale remains unclear. Using 4673 range shift estimates for 1888 species, we show that higher genetic diversity reduces trailing edge contractions under rapid warming and accelerates leading edge expansions under moderate ...
Brunno F. Oliveira, Romain Bertrand, Lise Comte, Jonathan Lenoir, Gaël Grenouillet, Lesley T. Lancaster, Jérôme Murienne, Sarah Diamond, Brett R. Scheffers, R. M. W. J. Bandara, Jake A. Lawlor, Nikki A. Moore, Barrett W. Wolfe, Fabricio Villalobos, Sarah R. Weiskopf, Laura M. Thompson, Malin L. Pinsky, Jonathan Rolland   +17 more
wiley   +1 more source

Structural and Genomic Bases of Branching Traits in Spur-Type Apple: Insights from Morphology and Whole-Genome Resequencing. [PDF]

Genes (Basel)
Wang H, Chen D, Zhao G, Zhang D, Liu X, Zhu B, Jia L, Zhao T, Zhang C, Zhang X.   +9 more
europepmc   +1 more source

Mechanical loading induces the longitudinal growth of muscle fibers via a rapamycin-insensitive mechanism. [PDF]

Sci Adv
Hibbert JE, Jorgenson KW, Sayed RKA, Paez HG, Meinhold M, Flynn CGK, Lange AN, Lindley GT, Flejsierowicz PM, Hornberger TA.   +9 more
europepmc   +1 more source

Rural Health Services Disruption: An Evaluation of Nursing's Professional ‘Positionality’

Nursing Philosophy, Volume 27, Issue 2, April 2026.
ABSTRACT Rural health services disruption poses a significant global challenge, with nurses at the forefront of its impact. From supply chain disruptions and workforce shortages to climate events and demographic shifts, these challenges consistently threaten the provision of healthcare in rural areas.
Jessica G. Smith, Sharon Laver
wiley   +1 more source