Results 141 to 150 of about 40,674 (185)

Transcription Regulatory Sequences in Coronaviruses: Mechanistic Foundations for Antivirals and Vaccines. [PDF]

J Microbiol Biotechnol
Myoung J.
europepmc   +1 more source

Development of RNA Aptamers That Inhibit the RNA-Dependent RNA Polymerase Activity of SARS-CoV-2 Strains In Vitro. [PDF]

Int J Mol Sci
Song C, Lee SW.
europepmc   +1 more source

Fusion Strategy of DNA-Encoded Libraries Drives Discovery of Allosteric Inhibitors of SARS-CoV‑2 RdRp. [PDF]

JACS Au
Li L, Wang X, Ding P, Shen X, Hu H, Wang X, Jin R, Wu X, Zhang Y, Lu W, Yue J, Xu HE, Yin W, Xu Y, Lu X.   +14 more
europepmc   +1 more source

ZNF219 inhibits porcine epidemic diarrhea virus by degrading viral S2 protein. [PDF]

Virol Sin
Zhao W, Kong N, Lan D, Zhang Y, Liu H, Liu C, Qin W, Yang X, Liu T, Tong W, Yu H, Zheng H, Tong G, Xie S, Xing G, Shan T.   +15 more
europepmc   +1 more source

Copy-back RNA synthesis by coronavirus polymerase requires helicase activity and is stimulated by remdesivir and molnupiravir. [PDF]

Sci Adv
Rakib A, Das A, Bera SC, Cnossen J, Robles-Sikisaka R, Diefenbacher MV, America PPB, Klein M, Anderson TK, Marecki JC, Wang B, Bogers E, Feng JY, Bilello JP, Papini FS, Smitskamp Q, Sheahan TP, Arnold JJ, Routh A, Artsimovitch I, Kirchdoerfer RN, Cameron CE, Raney KD, Dulin D.   +23 more
europepmc   +1 more source

Molecular Insights into High-Pathogenicity RNA Viruses. [PDF]

Viruses
Krnjić H, Hrapović A, Galijatović A, Tipura A, Hajdarpašić M, Kozarić S, Berilo A, Odobašić N, Hromić-Jahjefendić A, Šutković J.   +9 more
europepmc   +1 more source

Nucleocapsid protein captures DDX5 and RNMT facilitating viral RNA synthesis and viral protein translation for coronavirus replication. [PDF]

mBio
Liu Y, Kong N, Yang X, Qin W, Wang Y, Wang C, Sun H, Wang J, Gao A, Zheng D, Tong W, Yu H, Zheng H, Tong G, Shan T.   +14 more
europepmc   +1 more source

Polypeptide encoded by the -1 PRF signal of SARS-CoV-2 controls multiple enzymatic activities of the viral NiRAN domain. [PDF]

NAR Mol Med
Hsu HT, Cho CP, Lin CL, Chang KY.
europepmc   +1 more source

Preferential remdesivir triphosphate incorporation by SARS-CoV-2 polymerase is altered to ATP by the S759A mutation. [PDF]

Commun Biol
Gordon CJ, Oliva MF, Lee HW, Goovaerts Q, De Wijngaert B, Götte M, Das K.   +6 more
europepmc   +1 more source

Slow PP_i release enhances fidelity of the SARS-CoV-2 RNA dependent RNA polymerase. [PDF]

J Biol Chem
Dangerfield TL, Marko I, Johnson KA.
europepmc   +1 more source