Results 41 to 50 of about 16,210 (241)

NTCP structure and mRNA expression. [PDF]

open access: yes, 2017
(A) Structure of human NTCP (hNTCP). An HA tag was present at the cell surface exposed N-terminus. N-linked glycosylation sites are indicated. (B) NTCP mRNA expression in HepG2 cells expressing NTCP-WT, NTCP-N5Q, NTCP-N11Q or NTCP-N5,11Q analysed by qRT ...
Stan F. J. van de Graaf (486942)   +4 more
core   +1 more source

KIF4 regulates the surface NTCP expression. [PDF]

open access: yes, 2022
(A) HepG2-hNTCP were transfected with either si-control or si-KIF4 (si-1) and incubated for 72 h; the cells were then lysed and the expressions of total NTCP (upper panel), KIF4 (middle panel), and β-actin (loading control) (lower panel) were examined in
Hussein H. Aly (12269985)   +17 more
core   +1 more source

N-Glycosylation of the Na+-Taurocholate Cotransporting Polypeptide (NTCP) Determines Its Trafficking and Stability and Is Required for Hepatitis B Virus Infection.

open access: yesPLoS ONE, 2017
The sodium/bile acid cotransporter NTCP was recently identified as a receptor for hepatitis B virus (HBV). NTCP is glycosylated and the role of glycans in protein trafficking or viral receptor activity is not known.
Monique D Appelman   +4 more
doaj   +1 more source

Curcumin inhibited hepatitis B viral entry through NTCP binding

open access: yesScientific Reports, 2021
Hepatitis B virus (HBV) has been implicated in hepatitis and hepatocellular carcinoma. Current agents (nucleos(t)ide analogs and interferons) could only attenuate HBV infection. A combination of agents targeting different stages of viral life cycle (e.g.,
Piyanoot Thongsri   +5 more
semanticscholar   +1 more source

Strengthening National Tobacco Control Program (NTCP) to advance tobacco control (TC) policy in Uttar Pradesh (UP) [PDF]

open access: yes, 2018
Background and challenges to implementation Government of India launched NTCP in 2007-08 to create awareness about ill-effects of tobacco, enforcement of Cigarette and other Tobacco Product Act (COTPA) and regulate tobacco consumption.
Rajesh Ranjan, Sukriti Jain
core   +1 more source

Analytical investigation of properties of the iso-NTCP envelope [PDF]

open access: yesRadiology and Oncology, 2007
Background. A property of the integral dose-volume histogram (DVH) space is analytically investigated in this work. A curve called an α-iso-NTCP (normal tissue complication probability) envelope is constructed by connecting points belonging to step-like integral DVHs, each corresponding to homogeneous partial organ irradiation of a relative volume vk ...
Fallone, B. Gino   +4 more
openaire   +2 more sources

Estimated normal tissue complication probabilities (NTCP). [PDF]

open access: yes, 2016
NTCP values of xerostomia (upper) and dysphagia (lower) are shown per patient for IMRT (blue), 3-field minimax IMPT (gray) and 5-field minimax IMPT (green).
Lisanne V. van Dijk (2586112)   +6 more
core   +1 more source

The Use of Normal Tissue Complication Probability (NTCP) Models in the Clinic

open access: yesInternational Journal of Radiation Oncology, Biology, Physics, 2010
The QUANTEC (quantitative analysis of normal tissue effects in the clinic) review summarizes the currently-available three dimensional dose/volume/outcome data to update and refine the normal tissue dose/volume tolerance guidelines provided by the ...
L. Marks   +8 more
semanticscholar   +1 more source

Substrate Specificities and Inhibition Pattern of the Solute Carrier Family 10 Members NTCP, ASBT and SOAT

open access: yesFrontiers in Molecular Biosciences, 2021
Three carriers of the solute carrier family SLC10 have been functionally characterized so far. Na+/taurocholate cotransporting polypeptide NTCP is a hepatic bile acid transporter and the cellular entry receptor for the hepatitis B and D viruses.
G. Grosser   +4 more
semanticscholar   +1 more source

Effect of N-linked glycosylation on NTCP protein expression. [PDF]

open access: yes, 2017
(A and B) HA-tagged NTCP was immunoprecipitated (IP) from lysates of HepG2 cells stably expressing NTCP-WT, NTCP-N5Q, NTCP-N11Q or NTCP-N5,11Q. IP samples were subjected to immunoblotting for NTCP (using anti-HA-hrp).
Stan F. J. van de Graaf (486942)   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy