Results 61 to 70 of about 9,177 (185)

An NTCP Analysis of Urethral Complications from Low Doserate Mono- and Bi-Radionuclide Brachytherapy

Prostate Cancer, 2011
Urethral NTCP has been determined for three prostates implanted with seeds based on 125I (145 Gy), 103Pd (125 Gy), 131Cs (115 Gy), 103Pd-125I (145 Gy), or 103Pd-131Cs (115 Gy or 130 Gy).
V. E. Nuttens, A. E. Nahum, S. Lucas
doaj   +1 more source

A review of xenobiotic membrane transporter expression within the human placenta: Lessons gained from primary tissue and in vitro methodologies

The Journal of Physiology, EarlyView.
Abstract figure legend A summary of the current knowledge around membrane transporter expression in the most widely used in vitro models of human trophoblasts, including primary placental tissue, cancer cell lines and trophoblast stem cells, as well as the techniques to attempt to mimic the human placenta in vivo.
Rhiannon Pass, Kathryn Wolton, Amanda N. Sferruzzi‐Perri   +2 more
wiley   +1 more source

Use of Indocyanine Green (ICG), a Medical Near Infrared Dye, for Enhanced Fluorescent Imaging—Comparison of Organic Anion Transporting Polypeptide 1B3 (OATP1B3) and Sodium-Taurocholate Cotransporting Polypeptide (NTCP) Reporter Genes

Molecules, 2019
Molecular and cellular imaging in living organisms have ushered in an era of comprehensive understanding of intracellular and intercellular events. Currently, more efforts have been focused on the infrared fluorescent dyes that facilitate deeper tissue ...
Menq-Rong Wu, Yi-You Huang, Jong-Kai Hsiao   +2 more
doaj   +1 more source

Assessment of dose distribution in pancreatic SABR in the presence of a metallic biliary stent using Monte Carlo modeling

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background Stereotactic ablative radiotherapy (SABR) with dose escalation is increasingly used for pancreatic cancer; however, the dosimetric impact of metallic biliary stents remains poorly characterized. Self‐expanding metal stents (SEMS), commonly placed for obstructive jaundice, contain high‐density nitinol that produces computed ...
Ahmad Abbas, Owen Nicholas, Richard P. Hugtenburg   +2 more
wiley   +1 more source

Surface‐Guided Radiotherapy for Vulvar Cancer in the Frog‐Leg Position: Setup Accuracy and BMI Effects

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background Radiotherapy for vulvar carcinoma often employs the “frog‐leg” position to minimize skin toxicity, but this position is biomechanically unstable and prone to setup errors using conventional skin markings. Purpose To evaluate the clinical efficacy of Surface‐Guided Radiotherapy (SGRT) for setup accuracy in vulvar cancer patients ...
Hao Liang, Junfang Yan, Yongguang Liang, Xiansong Sun, Hongming Li, Huiying Qu, Yijun Wang, Jingyu Lin   +7 more
wiley   +1 more source

A mechanistic‐based normal tissue complication probability (NTCP) prediction through a microdosimetry‐based multiscale radiation biophysical model (MS‐GSM2)

Precision Radiation Oncology, EarlyView.
Marco Battestini, Marta Missiaggia, Giulio Bordieri, Jules Morand, Emanuele Scifoni, Francesco Giuseppe Cordoni   +5 more
wiley   +1 more source

Dosimetric and clinical validation of a high‐density bolus for superficial skin tumors treated with radiotherapy

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background Accurate dose deposition in superficial radiotherapy remains challenging due to the inherent skin‐sparing effect of megavoltage photon beams and difficulties in ensuring bolus conformity. Purpose This study aims to comprehensively evaluate the dosimetric characteristics of the room‐temperature‐malleable high‐density bolus, to ...
Jonathan Dadoun, Ann Van Esch, Noemie Litrowski, Carine Lefrancois‐Clement, Erwan Luce, Alexis Thelie, Nassima Delhoumi, Andrea Feuillet, Nesrine Zemman, Romain Mallet, Renata Pereira, Laurent Martin, Paul Gangloff, Christophe Moure, Luc Ollivier, Paul Lesueur   +15 more
wiley   +1 more source

Hepatitis B virus-targeting sodium taurocholate cotransporting polypeptide mediates HBV infection and damage in human renal podocytes

Microbiology Spectrum
Hepatitis B virus (HBV) may directly infect human podocytes (HPCs). However, the mechanism of direct infection is unclear. We found that HPCs express sodium taurocholate cotransporting polypeptide (NTCP), a specific receptor for HBV entry into ...
Lifen Wang, Cheng Wang, Xu Wang, Yantao Cao, Xiaohua Guo, Zhiming Ye   +5 more
doaj   +1 more source

Evaluating synthetic CT from deformable registration in directed adaptive radiotherapy for head and neck cancer

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background and purposel Anatomical changes over the many weeks of radiotherapy for Head and Neck cancer patients can compromise the original treatment plan, potentially increase the risk of side effects and impact outcomes. It is difficult to decide, based on daily imaging alone, which patients will most benefit from adapted treatment plans ...
Jessica Lye, Kartik Kumar, Benjamin Harris, Jarrod Prohasky, Leah McDermott, Simon Goodall, Jothy Selvaraj, Lauren Natoli, Morikatsu Wada, Sweet Ping Ng   +9 more
wiley   +1 more source

A dosimetric study of photon energy and flattening filter mode combinations in Stereotactic Central Ablative Radiotherapy

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background In Stereotactic Central Ablative Radiotherapy (SCART), the volume of tumor receiving the full prescribed ablative dose decreases rapidly as the prescription dose increases, posing a critical challenge. To address this issue, this study investigates the dosimetric impact of combining various photon energies and flattening filter ...
Jianwei Sun, Binghua Liang, Shiqiang Zhang, Heng Zhang, Shi Wang, Xinye Ni   +5 more
wiley   +1 more source