Results 81 to 90 of about 9,177 (185)

Photon minibeam‐based LATTICE radiotherapy for small and medium‐sized tumors: A dosimetric planning study

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Lattice radiotherapy (LRT) is a spatially fractionated technique that delivers three‐dimensional high‐dose vertices within tumors. However, conventional LRT is constrained by geometric limitations when applied to small and medium‐sized tumor volumes, primarily due to the large beam sizes that restrict optimal lattice pattern ...
Wei Wu, Nimita Shinde, Jiaxin Li, Isabelle Vanhaezebrouck, Kai Jiang, Yuting Lin, Qiang Li, Hao Gao   +7 more
wiley   +1 more source

Insufficient evidence for NTCP activity in stellate cells [PDF]

Gut, 2021
Roni F Kunst, Coen C Paulusma, Stan F J van de Graaf   +2 more
openaire   +3 more sources

Translational tumor control probability modeling for NSCLC: A two‐dimensional maximum‐likelihood framework

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Tumor control probability (TCP) modeling for early‐stage non‐small cell lung cancer (NSCLC) is usually performed by one‐dimensional (1D) fitting that assumes error‐free dose and assigns all uncertainty to the local control (LC) axis.
Ryoichi Hinoto, Takeji Sakae, Kenta Takada, Takahisa Eriguchi, Masashi Mizumoto, Atsuya Takeda, Hideyuki Sakurai   +6 more
wiley   +1 more source

Identification of amino acids restricting HBV receptor function in porcine NTCP

npj Viruses
With 254 million chronically infected patients, hepatitis B virus (HBV) continues to be a severe health threat. While animal models play a crucial role in developing new therapies, the availability of preclinical HBV models is very limited.
Samuel D. Jeske, Jochen M. Wettengel, Florian Gegenfurtner, Konrad Fischer, Judith Moosmüller, Anindita Chakraborty, Chunkyu Ko, Benjamin J. Burwitz, Angelika Schnieke, Ulrike Protzer   +9 more
doaj   +1 more source

Diverse Effects of the NTCP p.Ser267Phe Variant on Disease Progression During Chronic HBV Infection and on HBV preS1 Variability

Frontiers in Cellular and Infection Microbiology, 2019
The sodium taurocholate co-transporting polypeptide (NTCP) acts as a cellular receptor for the hepatitis B virus (HBV) infection on host hepatocytes.
Fangji Yang, Lina Wu, Wenxiong Xu, Ying Liu, Limin Zhen, Gang Ning, Jie Song, Qian Jiao, Yongyuan Zheng, Tongtong Chen, Chan Xie, Chan Xie, Liang Peng, Liang Peng   +13 more
doaj   +1 more source

Using Pharmacovigilance Data for Signal Detection of Drug Interactions for Rosuvastatin

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.
ABSTRACT The 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase inhibitor rosuvastatin is a substrate of breast cancer resistance protein (BCRP). BCRP inhibition increases rosuvastatin plasma concentrations and may result in concentration‐dependent muscle toxicity, at worst rhabdomyolysis.
Ronja Levomäki, Päivi Hirvensalo, Aleksi Tornio, Anne M. Filppula   +3 more
wiley   +1 more source

Development of a normal tissue complication probability (NTCP) model for radiation-induced hypothyroidism in nasopharyngeal carcinoma patients

BMC Cancer, 2018
Background The objectives of this study were to build a normal tissue complication probability (NTCP) model of radiation-induced hypothyroidism (RHT) for nasopharyngeal carcinoma (NPC) patients and to compare it with other four published NTCP models to ...
Ren Luo, Vincent W. C. Wu, Binghui He, Xiaoying Gao, Zhenxi Xu, Dandan Wang, Zhining Yang, Mei Li, Zhixiong Lin   +8 more
doaj   +1 more source

From Diagnosis to Durability: A Review of the European Bulevirtide Experience and Practical Learnings for CHD Management

Liver International, Volume 46, Issue 8, August 2026.
ABSTRACT Hepatitis delta virus (HDV) infection causes chronic hepatitis D (CHD), the most severe form of chronic viral hepatitis with a high risk of progression to advanced liver disease. Off‐label pegylated interferon alpha was the primary treatment option in Europe prior to the introduction of bulevirtide, a first‐in‐class HDV entry inhibitor.
Monica Radu, Margarita Papatheodoridi, Habiba Kamal Khodir, Sabela Lens, Elisabetta Degasperi, Speranta Iacob, Liliana Gheorghe, Katja Steppich, Florin Alexandru Caruntu, Pietro Lampertico, Soo Aleman, Heiner Wedemeyer   +11 more
wiley   +1 more source

Estimating how contouring differences affect normal tissue complication probability modelling

Physics and Imaging in Radiation Oncology
Background and purpose: Normal tissue complication probability (NTCP) models are developed from large retrospective datasets where automatic contouring is often used to contour the organs at risk.
Miguel Garrett Fernandes, Johan Bussink, Robin Wijsman, Barbara Stam, René Monshouwer   +4 more
doaj   +1 more source

Impact of India's National Tobacco Control Programme on bidi and cigarette consumption: a difference-in-differences analysis

Tobacco Induced Diseases, 2018
Background Notwithstanding the importance of decreasing tobacco use to achieve Sustainable Development Goals' mortality reduction targets, evaluations of tobacco control programmes in low- and middle-income settings are scarce.
Gaurang P. Nazar, Swati Srivastava, Kiara Chang, Neil Pearce, Anup Karan, Christopher Millett   +5 more
doaj   +1 more source