Results 131 to 140 of about 6,848 (195)

Heme-iron status influences disease severity of NTHI.

, 2013
Middle ear pressure was measured by tympanometry (mean ± S.D.) on each day following transbullar introduction of heme-iron replete (black squares) or restricted (gray circles) NTHI (A).
Blake R. Szelestey (469458), Sheryl S. Justice (176322), Forrest K. Raffel (340366), Kevin M. Mason (340370), Derek R. Heimlich (469459)   +4 more
core   +1 more source

Macrophage inflammatory responses to Non-typeable Haemophilus influenzae (NTHi) are strain-dependent

, 2019
The airway macrophage is crucial for immune surveillance and pathogen clearance, however, this function is impaired in chronic respiratory diseases such as COPD and asthma.
Cleary, David W., Staples, Karl J., David W Cleary, Spalluto, C. Mirella, Osman, Karen, Christodoulides, Myron, Karen Osman, Tom Wilkinson, Ackland, Jodie, Karl J Staples, Jodie Ackland, Cleary, David W.; id_orcid, Wilkinson, Tom, Myron Christodoulides, C. Mirella Spalluto   +14 more
core   +1 more source

A multi-iron enzyme installs copper-binding oxazolone/thioamide pairs on a nontypeable Haemophilus influenzae virulence factor

Proceedings of the National Academy of Sciences of the United States of America
Significance Nontypeable Haemophilus influenzae (NTHi) is a human pathogen that causes ear and lung infections. Unlike typeable H. influenzae, which is targeted by the Hib vaccine, NTHi remains a human health threat. We report that an essential virulence
Olivia M. Manley, Tucker J. Shriver, Tian Xu, Isaac A Melendrez, Philip M. Palacios, Scott A. Robson, Yisong Guo, Neil L. Kelleher, Joshua J. Ziarek, A. Rosenzweig   +9 more
semanticscholar   +1 more source

Oropharyngeal carriage of hpl-containing Haemophilus haemolyticus predicts lower prevalence and density of NTHi colonisation in healthy adults

, 2021
Nontypeable Haemophilus influenzae (NTHi) is a major respiratory pathogen that initiates infection by colonising the upper airways. Strategies that interfere with this interaction may therefore have a clinically significant impact on the ability of NTHi ...
David Gell (14737321), Brianna Atto (15432401), Stephen Tristram (14751343), Kunde, D (15562145)   +3 more
core  

Comparison of the adherence of nontypeable haemophilus influenzae to lung epithelial cells

BMC Infectious Diseases
Objective Nontypeable Haemophilus influenzae (NTHi) plays an important role in respiratory tract infections, and adherence to lung epithelial cells is the first step in lung infections.
Yuwei Rong, Zihao Liu, Heping Wang, Zuguo Zhao   +3 more
doaj   +1 more source

Whole-genome and pan-genome analyses reveal genomic differences among nontypeable <i>Haemophilus influenzae</i> isolates from bronchiectasis, community-acquired pneumonia, and chronic obstructive pulmonary disease. [PDF]

Front Cell Infect Microbiol
Hou T, Gao QH, Zhang QL, Zhou SJ, Zhang L, He QL, Cheng LP, Zhang N, Guan T, Yang YY, Li XR, He J.   +11 more
europepmc   +1 more source

Mucosal immune cell priming by intranasally delivered <i>Haemophilus haemolyticus</i> is associated with heterologous protection against influenza and nontypeable <i>Haemophilus influenzae</i>. [PDF]

Front Immunol
Pepper JS, Granland CM, Clark SL, Thornton RB, Bayliss J, Foo MZE, Billingham W, Scott N, Fulurija A, Strickland DH, Wiertsema SP, Richmond PC, Seppanen EJ, Kirkham LS, Tjiam MC.   +14 more
europepmc   +1 more source

Live nontypeable Haemophilus influenzae exacerbates respiratory syncytial virus-associated lower airway inflammation. [PDF]

Respir Res
Kawahara E, Morimoto K, Islam MS, Yamada H, Sekiguchi T, Morita M, Mitsuyama J, Morinaga Y.   +7 more
europepmc   +1 more source

Clinical Characteristics and Molecular Epidemiology of Invasive Nontypeable <i>Haemophilus influenzae</i> at a Tertiary Medical Center in Washington, DC. [PDF]

Open Forum Infect Dis
Lucar J, Stone S, Spence M, Siegel MO, Roberts A, Palmore TN, Ruiz ME, Saleem H, Lohsen S, Royer CJ, Collins LF, Yee R, Satola SW.   +12 more
europepmc   +1 more source

Multidrug resistance and genomic characteristics of nontypeable <i>Haemophilus influenzae</i> isolates from the respiratory tract of pediatric patients. [PDF]

Microbiol Spectr
Wen Z, Kong Y, Ling M, Zhang J, Du B, Yu Z, Yan C, Xue G, Gan L, Feng J, Fan Z, Fu T, Xu Z, Yang Y, Zhang T, Feng Y, Zhao H, Cui J, Yuan J.   +18 more
europepmc   +1 more source