WDR5 Facilitates Human Cytomegalovirus Replication by Promoting Capsid Nuclear Egress [PDF]
ABSTRACT WD repeat-containing protein 5 (WDR5) is essential for assembling the VISA-associated complex to induce a type I interferon antiviral response to Sendai virus infection. However, the roles of WDR5 in DNA virus infections are not well described.
Bo, Yang +16 more
openaire +2 more sources
XMM-Newton X-ray spectroscopy of the high-mass X-ray binary 4U1700-37 at low flux [PDF]
We present results of a monitoring campaign of the high-mass X-ray binary system 4U 1700-37/HD 153919, carried out with XMM-Newton in February 2001. The system was observed at four orbital phase intervals, covering 37% of one 3.41-day orbit.
A. van der Meer +65 more
core +2 more sources
A Role for Myosin Va in Human Cytomegalovirus Nuclear Egress. [PDF]
ABSTRACT Herpesviruses replicate and package their genomes into capsids in replication compartments within the nuclear interior. Capsids then move to the inner nuclear membrane for envelopment and release into the cytoplasm in a process called nuclear egress.
Wilkie AR +5 more
europepmc +4 more sources
UBVRI photopolarimetry of the long period eclipsing AM Herculis binary V1309 [PDF]
We report simultaneous UBVRI photo-polarimetric observations of the long period (7.98 h) AM Her binary V1309 Ori. The length and shape of the eclipse ingress and egress varies from night to night. We suggest this is due to the variation in the brightness
Anderlucci, E. +8 more
core +2 more sources
Primary envelopment of Kaposi’s sarcoma-associated herpesvirus at the nucleoplasmic reticulum
Herpesvirus egress begins with primary envelopment of newly assembled capsids at the inner nuclear membrane (INM). Primary envelopment has been observed at the peripheral INM as well as nuclear infoldings. Nuclear infoldings from invaginations of the INM
Alexa Wilson +2 more
doaj +1 more source
Mutational Functional Analysis of the Pseudorabies Virus Nuclear Egress Complex-Nucleocapsid Interaction. [PDF]
Herpesviruses encode an exceptional vesicle formation and scission machinery, which operates at the inner nuclear membrane, translocating the viral nucleocapsid from the nucleus into the perinuclear space. The conserved herpesviral nuclear egress complex (NEC) orchestrates this process.
Rönfeldt S +4 more
europepmc +4 more sources
Transit Lightcurve Signatures of Artificial Objects [PDF]
The forthcoming space missions, able to detect Earth-like planets by the transit method, will a fortiori also be able to detect the transit of artificial planet-size objects.
Luc F. A. Arnold, Tarter J.
core +3 more sources
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
No periodicity revealed for an "eclipsing" ultraluminous supersoft X-ray source in M81
Luminous supersoft X-ray sources found in the Milky Way and Magellanic Clouds are likely white dwarfs that steadily or cyclically burn accreted matter on their surface, which are promising type Ia supernova progenitors.
Dworetsky M. +3 more
core +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source

