Results 101 to 110 of about 6,512,295 (115)

Brefeldin A inhibits duck plague virus replication by impairing virion envelopment. [PDF]

open access: yesPoult Sci
Wang X   +19 more
europepmc   +1 more source

Cyclin-Dependent Kinase 8 Represents a Positive Regulator of Cytomegalovirus Replication and a Novel Host Target for Antiviral Strategies. [PDF]

open access: yesPharmaceutics
Obergfäll D   +20 more
europepmc   +1 more source

The conserved core nuclear egress complex (NEC) as an antiherpesviral drug target: Pharmacophore-based identification of NEC-specific inhibitors

Antiviral Research
The nucleocytoplasmic capsid egress of herpesviruses is a uniquely regulated process. As well-established for the human cytomegalovirus (HCMV) core nuclear egress complex (NEC), the pUL50-pUL53 NEC heterodimer oligomerizes and builds hexameric lattices for the regulated nucleocytoplasmic release of viral capsids.
Heinrich Sticht   +2 more
exaly   +3 more sources

The Knowns and Unknowns of Herpesvirus Nuclear Egress [PDF]

open access: yesAnnual Review of Virology, 2023
Nuclear egress of herpesvirus capsids across the intact nuclear envelope is an exceptional vesicle-mediated nucleocytoplasmic translocation resulting in the delivery of mature herpesvirus capsids into the cytosol.
Thomas C Mettenleiter, Barbara G Klupp
exaly   +2 more sources

Mutational Functional Analysis of the Pseudorabies Virus Nuclear Egress Complex-Nucleocapsid Interaction

open access: yesJournal of Virology, 2020
Herpesvirus nucleocapsids leave the nucleus by a vesicle-mediated translocation coordinated by the viral nuclear egress complex (NEC). The NEC, composed of two conserved viral proteins, designated as pUL34 and pUL31 in the alphaherpesvirus pseudorabies ...
Julia Holper   +2 more
exaly   +2 more sources

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