Results 31 to 40 of about 1,784 (124)

Viruses and Nuclear Egress [PDF]

, 2022
This Special Issue of Viruses focuses on the topic of viruses and nuclear egress. Nuclear egress is a fascinating process by which herpesvirus nucleocapsids make their way from the nuclear interior to the cytoplasm.

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Varicella Zoster Virus ORF25 Gene Product: An Essential Hub Protein Linking Encapsidation Proteins and the Nuclear Egress Complex [PDF]

, 2011
Varicella zoster virus (VZV) ORF25 is a 156 amino acid protein belonging to the approximately 40 core proteins that are conserved throughout the Herpesviridae.
Arvin, Ann M., Baiker, Armin, Gersting, Soren W., Haas, Juergen, Haase, Rudolf, Lotz-Havla, Arnelie S., Muntau, Ania C., Pinto, Maria G. Vizoso, Pothineni, Venkata R., Sommer, Marvin, Woidy, Mathias   +10 more
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The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles [PDF]

, 2008
Copyright @ 2008 American Society for Microbiology.The production of virus-like particles (VLPs) constitutes a relevant and safe model to study molecular determinants of virion egress.
Altmeyer, R, Bruzzone, R, Chan, CM, Escriou, N, Kien, F, Lo, J, Nal, B, Nicholls, JM, Peiris, JSM, Siu, YL, Teoh, KT, Tsao, SW   +11 more
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The Complex Regulatory Role of Cytomegalovirus Nuclear Egress Protein pUL50 in the Production of Infectious Virus

Cells, 2021
The regulation of the nucleocytoplasmic release of herpesviral capsids is defined by the process of nuclear egress. Due to their large size, nuclear capsids are unable to traverse via nuclear pores, so that herpesviruses evolved to develop a vesicular ...
Sigrun Häge, Nicole Büscher, Victoria Pakulska, Friedrich Hahn, Annie Adrait, Steffi Krauter, Eva Maria Borst, Ursula Schlötzer-Schrehardt, Yohann Couté, Bodo Plachter, Manfred Marschall   +10 more
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HVint: a strategy for identifying novel protein-protein interactions in Herpes Simplex Virus Type 1 [PDF]

, 2016
Human herpesviruses are widespread human pathogens with a remarkable impact on worldwide public health. Despite intense decades of research, the molecular details in many aspects of their function remain to be fully characterized.
Albright, Antinone, Aranda, Bastian, Berman, Blohm, Booy, Brady, Brückner, Budayeva, Calderone, Calderwood, Cardone, Chabaud, Chabaud, Chatr-Aryamontri, Chen, Chen, Chentoufi, Chowdary, Coller, Conner, Connolly, Cristea, Dai, Dai, Daikoku, de Chassey, de Oliveira, DeBlasio, Deng, Desai, Desai, Desai, Deutsch, Douglas, Dufour, Durmuş Tekir, Döhner, Eisenberg, Engel, Folador, Fossum, Funk, Greco, Grünenfelder, Grünewald, Guirimand, Guo, Hagen, Hosur, Hosur, Jaeger, Kerrien, Klupp, Kobayashi, Kopp, Kopp, Kramer, Krautwald, Kshirsagar, Kulak, Langelier, Lawson, Lee, Leege, Lenk, Lin, Loomis, Loret, Lyman, López-Blanco, Lövheim, Marcoux, Marras, McDowall, Meckes, Mora, Murakami, Nagel, Nagel, Navlakha, Nourani, Nozawa, Orchard, Panagiotidis, Radtke, Ramisetty, Remmert, Reynolds, Rollenhagen, Roller, Roller, Rowles, Rozen, Saeed, Schnee, Sheaffer, Silva, Singh, Snijder, Snyder, Sprinzak, Stampfer, Stellberger, Stelzl, Sugimoto, Suzek, Szklarczyk, Taylor, The UniProt Consortium, Thomsen, To, Tomishima, Toropova, Trus, Trus, Uetz, Uetz, Villaveces, Vittone, Vizcaíno, Wills, Winterbach, Wnuk, Xenarios, Yang, Yeh, You, Yu, Zahiri, Zeev-Ben-Mordehai, Zhang, Zhou   +133 more
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Virus-derived peptide inhibitors of the herpes simplex virus type 1 nuclear egress complex

Scientific Reports, 2021
Herpesviruses infect a majority of the human population, establishing lifelong latent infections for which there is no cure. Periodic viral reactivation spreads infection to new hosts while causing various disease states particularly detrimental in the ...
Elizabeth B. Draganova, Ekaterina E. Heldwein   +1 more
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Subcellular Distribution of BALF2 and the Role of Rab1 in the Formation of Epstein-Barr Virus Cytoplasmic Assembly Compartment and Virion Release

Microbiology Spectrum, 2023
Epstein-Barr virus (EBV) replicates its genome in the nucleus and undergoes tegumentation and envelopment in the cytoplasm. We are interested in how the single-stranded DNA binding protein BALF2, which executes its function and distributes predominantly ...
Tsung-Yu Chao, Yi-Ying Cheng, Zi-Yun Wang, Tien-Fang Fang, Yu-Ruei Chang, Chi-Shane Fuh, Mei-Tzu Su, Yuan-Wei Su, Pang-Hung Hsu, Yu-Chen Su, Yu-Ching Chang, Ting-Yau Lee, Wei-Han Chou, Jaap M. Middeldorp, Jaakko Saraste, Mei-Ru Chen   +15 more
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pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread. [PDF]

, 2021
The herpes simplex virus (HSV)-1 protein pUL21 is essential for efficient virus replication and dissemination. While pUL21 has been shown to promote multiple steps of virus assembly and spread, the molecular basis of its function remained unclear.
Benedyk, Tomasz H, Brown, Katherine, Bryant, Neil A, Colaco, Susanna, Connor, Viv, Crump, Colin M, Deane, Janet E, Firth, Andrew E, Graham, Stephen C, Han, Yue, Jeffries, Cy M, Muenzner, Julia, Stoll, Guido A, Svergun, Dmitri I, Svobodova, Stanislava, Tutt, Owen S, Wijesinghe, Kaveesha J, Zhuang, Yunhui   +17 more
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Crystal Structure of the Herpesvirus Nuclear Egress Complex Provides Insights into Inner Nuclear Membrane Remodeling

Cell Reports, 2015
Although nucleo-cytoplasmic transport is typically mediated through nuclear pore complexes, herpesvirus capsids exit the nucleus via a unique vesicular pathway.
Tzviya Zeev-Ben-Mordehai, Marion Weberruß, Michael Lorenz, Juliana Cheleski, Teresa Hellberg, Cathy Whittle, Kamel El Omari, Daven Vasishtan, Kyle C. Dent, Karl Harlos, Kati Franzke, Christoph Hagen, Barbara G. Klupp, Wolfram Antonin, Thomas C. Mettenleiter, Kay Grünewald   +15 more
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Funktionelle Analyse herpesviraler nukleärer Egress-Komplexe - Determinanten der Replikationseffizienz und Zielmoleküle für neue antivirale Strategien [PDF]

, 2023
The nuclear egress of herpesviruses is a highly conserved process that regulates the nucleocytoplasmic capsid release. For the human cytomegalovirus (HCMV), the nuclear egress complex (NEC) is determined by the core proteins pUL50 and pUL53 that ...
Häge, Sigrun
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