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Mechanotransduction by nuclear envelope tension [PDF]
NucleusMechanotransduction mediated by the tension in lipid membranes is a well-established paradigm. This has been studied largely in the context of the plasma membrane, but recent work shows that it applies also to endomembranes, and specifically to the ...
Sriivatsan G. Rajan +2 more
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Nuclear Envelope Dynamics in Dictyostelium Amoebae [PDF]
CellsIn the last decades, the study of many nuclear envelope components in Dictyostelium amoebae has revealed conserved mechanisms of nuclear envelope dynamics that root back unexpectedly deep into the eukaryotic tree of life.
Ralph Gräf +4 more
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Nuclear envelope and chromatin choreography direct cellular differentiation [PDF]
NucleusThe nuclear envelope plays an indispensable role in the spatiotemporal organization of chromatin and transcriptional regulation during the intricate process of cell differentiation.
Anjitha Nair +4 more
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Cells, 2022 Any given cell type has an associated “normal” nuclear morphology, which is important to maintain proper cellular functioning and safeguard genomic integrity.
Anne F. J. Janssen +2 more
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Cells, 2023 The Amoebozoan Dictyostelium discoideum exhibits a semi-closed mitosis in which the nuclear membranes remain intact but become permeabilized to allow tubulin and spindle assembly factors to access the nuclear interior.
Kristina Mitic +3 more
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Automated analysis of cell migration and nuclear envelope rupture in confined environments. [PDF]
PLoS ONE, 2018 Recent in vitro and in vivo studies have highlighted the importance of the cell nucleus in governing migration through confined environments. Microfluidic devices that mimic the narrow interstitial spaces of tissues have emerged as important tools to ...
Joshua J Elacqua +2 more
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Recent advances in understanding the biological roles of the plant nuclear envelope
Nucleus, 2020 The functional organization of the plant nuclear envelope is gaining increasing attention through new connections made between nuclear envelope-associated proteins and important plant biological processes.
Norman Reid Groves +5 more
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Cell migration in dense microenvironments
Comptes Rendus Biologies, 2023 The nucleus has been viewed as a passenger during cell migration that functions merely to protect the genome. However, increasing evidence shows that the nucleus is an active organelle, constantly sensing the surrounding environment and translating ...
de Freitas Nader, Guilherme Pedreira +1 more
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Interplay of the nuclear envelope with chromatin in physiology and pathology
Nucleus, 2020 The nuclear envelope compartmentalizes chromatin in eukaryotic cells. The main nuclear envelope components are lamins that associate with a panoply of factors, including the LEM domain proteins.
Romina Burla +5 more
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Nuclear envelope budding and its cellular functions
Nucleus, 2023 The nuclear pore complex (NPC) has long been assumed to be the sole route across the nuclear envelope, and under normal homeostatic conditions it is indeed the main mechanism of nucleo-cytoplasmic transport.
Katharina S. Keuenhof +6 more
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