Results 11 to 20 of about 136,990 (241)
The Plant Nuclear Envelope and Its Role in Gene Transcription
Frontiers in Plant Science, 2021 Chromosomes are dynamic entities in the eukaryotic nucleus. During cell development and in response to biotic and abiotic change, individual sections as well as entire chromosomes re-organise and reposition within the nuclear space.
Jade Bishop +3 more
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Cells, 2023 Regulator of TElomere Length Helicase 1 (RTEL1) is a helicase required for telomere maintenance and genome replication and repair. RTEL1 has been previously shown to participate in the nuclear export of small nuclear RNAs.
Michael Schertzer +5 more
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eLife, 2020 The switch from centrosomal microtubule-organizing centers (MTOCs) to non-centrosomal MTOCs during differentiation is poorly understood. Here, we identify AKAP6 as key component of the nuclear envelope MTOC.
Silvia Vergarajauregui +10 more
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Cold Spring Harbor Perspectives in Biology, 2010 The nuclear envelope (NE) is a highly regulated membrane barrier that separates the nucleus from the cytoplasm in eukaryotic cells. It contains a large number of different proteins that have been implicated in chromatin organization and gene regulation.
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The nuclear envelopathies and human diseases
Journal of Biomedical Science, 2009 The nuclear envelope (NE) consists of two membrane layers that segregate the nuclear from the cytoplasmic contents. Recent progress in our understanding of nuclear-lamina associated diseases has revealed intriguing connections between the envelope ...
Jeang Kuan-Teh, Chen Zi-Jie, Chi Ya-Hui
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Cell Communication and Signaling, 2023 Fibroblast growth factor receptor 1 (FGFR1) is a heavily N-glycosylated cell surface receptor tyrosine kinase that transmits signals across the plasma membrane, in response to fibroblast growth factors (FGFs).
Paulina Gregorczyk +8 more
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Nuclear Envelope: Nuclear Pore Complexity [PDF]
Current Biology, 2005 A new study shows that the filamentous fungus, Aspergillus nidulans, which has a closed mitosis, does not maintain a continuous permeability barrier during mitosis. This work challenges current views of the differences between closed and open mitosis and has implications for understanding mitotic specific changes in the nuclear pore complex and Ran ...
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Nuclear envelope remnants: fluid membranes enriched in sterols and polyphosphoinositides.
PLoS ONE, 2009 BackgroundThe cytoplasm of eukaryotic cells is a highly dynamic compartment where membranes readily undergo fission and fusion to reorganize the cytoplasmic architecture, and to import, export and transport various cargos within the cell.
Marie Garnier-Lhomme +7 more
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Signal Transduction across the Nuclear Envelope: Role of the LINC Complex in Bidirectional Signaling
Cells, 2019 The primary functions of the nuclear envelope are to isolate the nucleoplasm and its contents from the cytoplasm as well as maintain the spatial and structural integrity of the nucleus.
Miki Hieda
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Nuclear Envelope Regulation of Oncogenic Processes: Roles in Pancreatic Cancer
Epigenomes, 2018 Pancreatic cancer is an aggressive and intractable malignancy with high mortality. This is due in part to a high resistance to chemotherapeutics and radiation treatment conferred by diverse regulatory mechanisms.
Claudia C. Preston +1 more
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