Results 11 to 20 of about 2,002,555 (370)

Nuclear Envelope: Nuclear Pore Complexity [PDF]

open access: yesCurrent Biology, 2005
A new study shows that the filamentous fungus, Aspergillus nidulans, which has a closed mitosis, does not maintain a continuous permeability barrier during mitosis. This work challenges current views of the differences between closed and open mitosis and
Sazer, Shelley
core   +5 more sources

Pushing the (nuclear) envelope into meiosis. [PDF]

open access: yesGenome Biology, 2013
A recent study shows that a short isoform of a mammalian nuclear lamin is important for homologous chromosome interactions during meiotic prophase in ...
Dernburg, Abby F
core   +7 more sources

Nuclear Envelope, Nuclear Lamina, and Inherited Disease [PDF]

open access: yes, 2005
The nuclear envelope is composed of the nuclear membranes, nuclear lamina, and nuclear pore complexes. In recent years, mutations in nuclear-envelope proteins have been shown to cause a surprisingly wide array of inherited diseases.
Courvalin, Jean-Claude, Worman, Howard,
core   +9 more sources

Temporal Changes in Nuclear Envelope Permeability during Semi-Closed Mitosis in Dictyostelium Amoebae

open access: yesCells, 2023
The Amoebozoan Dictyostelium discoideum exhibits a semi-closed mitosis in which the nuclear membranes remain intact but become permeabilized to allow tubulin and spindle assembly factors to access the nuclear interior.
Kristina Mitic   +3 more
doaj   +1 more source

Direct binding of ESCRT protein Chm7 to phosphatidic acid–rich membranes at nuclear envelope herniations

open access: yesJournal of Cell Biology, 2021
Thaller et al. demonstrate that direct binding between phosphatidic acid (PA) and the ESCRT Chm7 is required for nuclear envelope surveillance; PA also accumulates at nuclear envelope herniations.
David J. Thaller   +8 more
semanticscholar   +1 more source

LEM2 phase separation governs ESCRT-mediated nuclear envelope reformation

open access: yesNature, 2020
During cell division, remodelling of the nuclear envelope enables chromosome segregation by the mitotic spindle1. The reformation of sealed nuclei requires ESCRTs (endosomal sorting complexes required for transport) and LEM2, a transmembrane ESCRT ...
Alexander von Appen   +7 more
semanticscholar   +1 more source

Dynein at the nuclear envelope [PDF]

open access: yesEMBO reports, 2010
Most cellular organelles are positioned through active transport by motor proteins. The authors discuss the evidence that dynein has important cell cycle‐regulated functions in this context at the nuclear envelope.
René H. Medema   +2 more
openaire   +5 more sources

Dystonia and the Nuclear Envelope [PDF]

open access: yesNeuron, 2005
Mutations in torsinA cause dominantly inherited early-onset torsion dystonia in humans. In this issue of Neuron, Goodchild et al. show that torsinA knockout and knockin mice have similar phenotypes, which suggests that the mutant torsinA allele causes disease because it has decreased function. The experiments also highlight the possible role of nuclear
Jordi Clarimón, Mark R. Cookson
openaire   +2 more sources

Nuclear envelope dysfunction and its contribution to the aging process

open access: yesAging Cell, 2020
The nuclear envelope (NE) is the central organizing unit of the eukaryotic cell serving as a genome protective barrier and mechanotransduction interface between the cytoplasm and the nucleus.
F. Martins   +4 more
semanticscholar   +1 more source

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