Results 11 to 20 of about 401,673 (204)
Nuclear Envelope, Nuclear Lamina, and Inherited Disease [PDF]
, 2005 The nuclear envelope is composed of the nuclear membranes, nuclear lamina, and nuclear pore complexes. In recent years, mutations in nuclear-envelope proteins have been shown to cause a surprisingly wide array of inherited diseases.
Courvalin, Jean-Claude, Worman, Howard,
core +9 more sources
The nuclear envelope and metastasis. [PDF]
Oncotarget, 2023 Hansen E, Holaska JM.
europepmc +3 more sources
Cells, 2022 Any given cell type has an associated “normal” nuclear morphology, which is important to maintain proper cellular functioning and safeguard genomic integrity.
Anne F. J. Janssen +2 more
doaj +1 more source
Cells, 2023 The Amoebozoan Dictyostelium discoideum exhibits a semi-closed mitosis in which the nuclear membranes remain intact but become permeabilized to allow tubulin and spindle assembly factors to access the nuclear interior.
Kristina Mitic +3 more
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Dystonia and the Nuclear Envelope [PDF]
Neuron, 2005 Mutations in torsinA cause dominantly inherited early-onset torsion dystonia in humans. In this issue of Neuron, Goodchild et al. show that torsinA knockout and knockin mice have similar phenotypes, which suggests that the mutant torsinA allele causes disease because it has decreased function. The experiments also highlight the possible role of nuclear
Jordi Clarimón, Mark R. Cookson
openaire +2 more sources
Dynein at the nuclear envelope [PDF]
EMBO reports, 2010 Most cellular organelles are positioned through active transport by motor proteins. The authors discuss the evidence that dynein has important cell cycle‐regulated functions in this context at the nuclear envelope.
René H. Medema +2 more
openaire +5 more sources
Automated analysis of cell migration and nuclear envelope rupture in confined environments. [PDF]
PLoS ONE, 2018 Recent in vitro and in vivo studies have highlighted the importance of the cell nucleus in governing migration through confined environments. Microfluidic devices that mimic the narrow interstitial spaces of tissues have emerged as important tools to ...
Joshua J Elacqua +2 more
doaj +1 more source
Cell migration in dense microenvironments
Comptes Rendus Biologies, 2023 The nucleus has been viewed as a passenger during cell migration that functions merely to protect the genome. However, increasing evidence shows that the nucleus is an active organelle, constantly sensing the surrounding environment and translating ...
de Freitas Nader, Guilherme Pedreira +1 more
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Recent advances in understanding the biological roles of the plant nuclear envelope
Nucleus, 2020 The functional organization of the plant nuclear envelope is gaining increasing attention through new connections made between nuclear envelope-associated proteins and important plant biological processes.
Norman Reid Groves +5 more
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The Plant Nuclear Envelope and Its Role in Gene Transcription
Frontiers in Plant Science, 2021 Chromosomes are dynamic entities in the eukaryotic nucleus. During cell development and in response to biotic and abiotic change, individual sections as well as entire chromosomes re-organise and reposition within the nuclear space.
Jade Bishop +3 more
doaj +1 more source