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Nuclear import and export pathways
Journal of Cellular Biochemistry, 1999Macromolecules enter or leave the nucleus by using nuclear localization signals (NLS), or nuclear export signals (NES), respectively. Different types of NLS and NES are recognized directly or indirectly via adapters, by transport receptors. All transport receptors identified thus far are members of the same family and share an ability to shuttle ...
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An RNA-export mediator with an essential nuclear export signal
Nature, 1996The Rev protein of human immunodeficiency virus type 1 (HIV-1) mediates the translocation of viral messenger RNAs from the nucleus to the cytoplasm. In yeast, Rev can mediate the nuclear export of Rev response-element-containing RNAs. The export of Rev itself proceeds through the nuclear pore complex and requires a nuclear export signal (NES) and ...
R, Murphy, S R, Wente
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Nuclear Export of Messenger RNA
2002Messenger RNAs (mRNAs) exist in the cell in dynamic association with multiple distinct proteins. The mRNA export cargo is therefore a ribonucleoprotein particle (mRNP). The most striking example of this are the Balbiani ring (BR) mRNPs of Chironomus tentans which are composed of an RNA molecule of 35–40 kb in length associated with about 500 protein ...
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Regulation of nuclear import and export
2001Publisher Summary An exchange of molecules between the nucleus and cytoplasm is indispensable for gene regulation and normal cell growth and development. Transcription of RNA from DNA occurs in the nucleus, while translation of RNA into protein occurs on cytoplasmic ribosomes. Many proteins rapidly shuttle between the nucleus and cytoplasm, and their
T D, Sweitzer, D C, Love, J A, Hanover
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Eukaryotic Ribosome Assembly and Nuclear Export
2015Accurate translation of the genetic code into functional polypeptides is key to cellular growth and proliferation. This essential process is carried out by the ribosome, a ribonucleoprotein complex of remarkable size and intricacy. Although the structure of the mature ribosome has provided insight into the mechanism of translation, our knowledge ...
Nerurkar Purnima +6 more
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International Security, 1978
The United States is now moving towards nonproliferation and nuclear export policies which will directly or tangentially affect the Soviet Union. Policymakers may be assuming that cooperation between the two countries on nuclear matters will be easy, and may be inclined to engage in a degree of mirror-imaging and wishful thinking about Soviet interests.
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The United States is now moving towards nonproliferation and nuclear export policies which will directly or tangentially affect the Soviet Union. Policymakers may be assuming that cooperation between the two countries on nuclear matters will be easy, and may be inclined to engage in a degree of mirror-imaging and wishful thinking about Soviet interests.
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Keeping mRNPs in check during assembly and nuclear export
Nature Reviews Molecular Cell Biology, 2011Françoise Stutz, Evelina Tutucci
exaly

